Paediatric Cutaneous Mastocytosis : Report of 3 Cases

Abstract

Mastocytosis occurs due to clonal, neoplastic proliferation of mast cells that accumulate in one or more organ systems. It is characterized by an abnormal mast cell infiltrates1 . It can be divided into cutaneous and systemic Mastocytosis. Mast cell infiltrates remain confined to skin in cutaneous Mastocytosis. Urticaria pigmentosa / Maculopapular cutaneous Mastocytosis , Diffuse cutaneous Mastocytosis and mastocytoma of skin are the 3 variants of cutaneous Mastocytosis. Systemic mastocytosis is characterized by the involvement of atleast one extracutaneous organ with or without evidence of skin lesions. This paper describes 3 cases of paediatric cutaneous mastocytosis.