Paediatric sedation for imaging is safe and effective in a district general hospital

Bailey, Matthew D.; Saraswatula, Arun; Dale, Gemma; Softley, Laura

doi:10.1259/bjr.20150483

Cited by 17 publications

(14 citation statements)

References 30 publications

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“…The literature supports sedation for paediatric MRI as effective and safe, with comparable success rates to our results, although there is no consensus on the methods of sedation . Common minor adverse events with sedation include vomiting and excessive secretions and apnoea; serious adverse events are very rare, with none reported here.…”

supporting

confidence: 76%

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Sedation for screening MRI in patients with congenital melanocytic naevi under the age of one is a successful, safe and economical first‐line approach

et al. 2018

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supporting

confidence: 76%

“…Common minor adverse events with sedation include vomiting and excessive secretions and apnoea; serious adverse events are very rare, with none reported here. Sedation is also cheaper than GA, at £462 vs. £770 per patient …”

mentioning

confidence: 99%

Sedation for screening MRI in patients with congenital melanocytic naevi under the age of one is a successful, safe and economical first‐line approach

et al. 2018

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“…Препарат назначается детям (включая детей 3-5 лет), страдающим нарушениями сна, и представляет альтернативу традиционным снотворным средствам, в том числе бензодиазепинам [20]. Алимемазин находит применение в качестве седативного средства в детской стоматологии [21] и (наряду с хлоралгидратом) может использоваться в качестве безопасного и эффективного средства достижения седации при проведении нейровизуализационных исследований в педиатрической практике [22]. Кроме того, алимемазин (в дополнение к барбитуратам) рассматривается в качестве безопасной альтернативы общей анестезии для детей в возрасте 2-5 лет [23].…”

Section: Yup Sivolap Sechenov First Moscow State Medical Universityunclassified

Anxiety associated with substance abuse

Sivolap

2016

Z. nevrol. psikhiatr. im. S.S. Korsakova

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Substance abuse and anxiety is a common comorbid dyad and an example of so-called dual diagnosis in psychiatry. Comorbidity of anxiety and addictive disorders may be due to interdependence of these states as well as common predisposing factors and pathogenic mechanisms. There are various medicines in the treatment of anxiety associated with substance abuse, including benzodiazepines, calcium channel modulators, non-benzodiazepine anxiolytics, antidepressants and antipsychotics. One of the best approaches to the treatment of chronic anxiety disorders in drug treatment clinic is a long course of treatment with antidepressants, primarily with selective serotonin reuptake inhibitors as first line preparations. Such medications as pregabalin, buspirone, etifoxine and alimemazine are also of interest for the treatment of dual diagnosis patients.

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“…In order to obtain useful data from accurate imaging without excessive radiation exposure, a child needs to be lain down during the scanning procedure. The imaging tests that are affected negatively by motion [computed tomography (CT) or magnetic resonance imaging] are the most common procedures for which children undergo sedation (1)(2)(3). Imaging can often be performed without sedation in older cooperative children and young infants (up to six months of age) who are swaddled and recently fed (1)(2)(3)(4).…”

Section: Introductionmentioning

confidence: 99%

Efficacy and Safety of Intranasal Midazolam Versus Chloral Hydrate as Sedation for Quality Computed Tomography Imaging in Children

Heydari¹,

Shabani²,

Majidinejad³

et al. 2019

jpr

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The purpose of this study was to compare the efficacy and safety of aerosolized intranasal midazolam (INM) compared to oral chloral hydrate (OCH) as procedural sedatives in pediatric patients undergoing computed tomography (CT) imaging. Materials and Methods: A prospective, randomized, double-blind clinical trial was utilized in children aged 1 to 8 years who presented to the ED with minor head trauma and were scheduled to undergo brain CT scan. One hundred and sixty children were randomized to receive INM 0.3 mg/kg with oral placebo or 75 mg/kg OCH with intranasal placebo. If the patient was not adequately sedated 20 minutes after the initial dose, a second dose of the same medication at one-third of the initial dosage was given. The sedation level of patients after drug administration was assessed using the Ramsay sedation scale. Results: Both groups were comparable with respect to age, male to female ratio, weight, and baseline vital signs. Sixty two children (77.50%) in the INM group and 59 children (73.42%) in the OCH groups reached a Ramsay score of four, respectively (p=0.55). There was no significant difference in regards to the time to become adequately sedated (21.32±6.54 vs 23.62±7.40, p=0.173) and time for completing CT scan (30.37±7.18 vs 32.96±7.85, p=0.185). However, the time to recovery was shorter for the INM group (72.52±10.17 vs 88.10±10.27, p=0.001). No serious side effects were seen in the study groups (p=0.836). The majority of parents were somewhat to very satisfied, 83.54% and 81.25% in the OCH and INM groups, respectively (p=0.928). Conclusion: INM can be used to sedate children between 1 to 8 years who are to undergo CT imaging of brain with a comparable rate of efficacy and safety to OCH.

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Paediatric sedation for imaging is safe and effective in a district general hospital

Abstract: There are many different sedation protocols in the literature for imaging in paediatric patients, with varying levels of success and adverse event rates. We present here a protocol that offers a high efficacy and safe sedation for imaging in a DGH.

Cited by 17 publications

References 30 publications

Sedation for screening MRI in patients with congenital melanocytic naevi under the age of one is a successful, safe and economical first‐line approach

Sedation for screening MRI in patients with congenital melanocytic naevi under the age of one is a successful, safe and economical first‐line approach

Anxiety associated with substance abuse

Efficacy and Safety of Intranasal Midazolam Versus Chloral Hydrate as Sedation for Quality Computed Tomography Imaging in Children

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