Sedation for screening MRI in patients with congenital melanocytic naevi under the age of one is a successful, safe and economical first‐line approach

Neuroimaging in infants and children in select neurocutaneous disorders

“…2 While nonpharmacological methods such as 'feed and wrap' can be effective at very young ages, sedation or general anaesthetic (GA) is frequently required between the ages of 3 months (or < 5 kg) and 6 years. 1,2 Some neurocutaneous disease guidelines assume that sedation is used rather than GA, 3 as it is less resource-intensive it avoids the neurodevelopmental concerns of GA (although evidence for this in humans is not compelling 4 ) and, although less effective than GA, high success rates have been reported (90-95%). 2,3 The need for sedation/GA may be influenced by the requirement for contrast, which poses its own risks.…”

“…1,2 Some neurocutaneous disease guidelines assume that sedation is used rather than GA, 3 as it is less resource-intensive it avoids the neurodevelopmental concerns of GA (although evidence for this in humans is not compelling 4 ) and, although less effective than GA, high success rates have been reported (90-95%). 2,3 The need for sedation/GA may be influenced by the requirement for contrast, which poses its own risks. 1 Although nephrogenic systemic fibrosis is rare in paediatric patients, there are concerns regarding the observation of gadolinium deposition throughout the body.…”