1980
DOI: 10.1136/bmj.280.6222.1105
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Paget's disease of bone: the Lancashire focus.

Abstract: could not be stated with any conviction for the patients in the retrospective study, many of whom died while still hypothermic and before a definite diagnosis was made.

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Cited by 151 publications
(58 citation statements)
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“…There is no evidence for the Lancashire focus noted in the disease today. (7,8) However, archaeological cemetery excavations from that area have been rather few.…”
Section: Resultsmentioning
confidence: 99%
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“…There is no evidence for the Lancashire focus noted in the disease today. (7,8) However, archaeological cemetery excavations from that area have been rather few.…”
Section: Resultsmentioning
confidence: 99%
“…This is concordant with results from modern populations, where a male sex bias generally (but not invariably) is reported. (7,8,(11)(12)(13) …”
Section: Resultsmentioning
confidence: 99%
“…The deformity is most visible in the skull and lower extremities. Symmetrical enlargement of the cranium may fi rst come to attention in those individuals (4,28). The spine is a common source of morbidity from Paget's disease.…”
Section: Resultsmentioning
confidence: 99%
“…En España un estudio multicéntrico de ámbito nacional estableció una prevalencia estimada entre el 1,1 y 1,6% en las personas mayores de 55 años (5). Además en varios países se han encontrado marcadas variaciones regionales con áreas o focos de alta prevalencia (6,7). Se ha descrito una agregación familiar entre un 15% y un 40% de los pacientes (8) y en estos casos la enfermedad se transmite de forma autosómica dominante con una penetrancia variable.…”
Section: La Enfermedad De Pagetunclassified