Pain, depression levels, fatigue, sleep quality, and quality of life inelderly patients with rheumatoid arthritis

Abstract

The aim of this study was to evaluate and determine the relationships (if any) among pain, depression levels, fatigue, sleep quality, and quality of life in patients with rheumatoid arthritis (RA) aged 65 years and over, and to compare the results with those of RA patients under 65 years of age. Materials and methods:The study included 52 patients with RA aged 65 years and over (Group 1) and 84 patients with RA under 65 years of age (Group 2). Pain, depression levels, fatigue, sleep quality, quality of life, and disease activity of all of the participants were evaluated using a visual analog scale (VAS),

A biopsychosocial network model of fatigue in rheumatoid arthritis: a systematic review

“…Cross-sectionally, univariate associations between low physical role functioning of the SF-36 and fatigue levels were significant in all [8–12, 14] but one [13] study; the median correlation was 0.51 (range 0.29–0.56). The multivariate association was significant in two studies [10, 11] and not significant in one study [13].…”

“…Cross-sectionally, univariate associations between low mental health (SF-36) and fatigue were significant in four studies, with a median correlation of 0.46 (range 0.38–0.76) [9, 10, 24, 31] and not significant in three studies [8, 12, 13]. The multivariate association was not significant in one study [13].…”

“…Cross-sectionally, univariate associations between low emotional role functioning (SF-36) and fatigue levels were significant in four studies, with a median correlation of 0.42 (range 0.35–0.85) [8, 9, 14, 24] and not significant in one univariate and multivariate analysis [13].…”

“…Cross-sectional univariate associations between higher pain and higher fatigue levels were significant, with a median correlation of 0.51 (range 0.22–0.75) in all studies [10, 12, 13, 15, 17–20, 24, 31, 39, 40, 50, 60–69], but there was one in which only one of two correlations was significant [8]. The multivariate association was significant after controlling for variables such as demographics, disease activity, depression, sleep and physical functioning in all studies [10, 17, 18, 32, 39, 50, 61, 63, 66, 70], but there was one that included another pain measure as a covariate [27].…”

“…In the reviewed studies, sleep disturbance was measured with self-report questionnaires. Cross-sectionally, all univariate associations between sleep disturbance and fatigue were significant but one [64], with a median correlation of 0.45 (range 0.21–0.66) [8, 10, 25, 27, 30–32, 49, 56, 67, 74–76]. With the exception of one study [77], the multivariate association remained significant after controlling for variables such as demographics, disease activity, pain and physical functioning [10, 25, 32, 49, 75, 76, 78].…”