Paleopharmacology and pollen: theory, method, and application

Chaves, Sérgio Augusto de Miranda; Reinhard, Karl J.

doi:10.1590/s0074-02762003000900030

Cited by 34 publications

(22 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Silva, unpublished data). In traditional medicine, the leaves of this species have been used to control diabetes (Chaves andReinhard 2003, Agra et al 2008) while the ethanol extract has inhibited the growth of Aspergillus niger and Fusarium oxysporum cultures (Rocha et al 2004). The antioxidant activity of M. hirsuta was also demonstrated by Braga et al (2000) while isolated proanthocyanidins were capable of inhibiting angiotensin-converting enzyme (ACE) (Campana et al 2009).…”

Section: Introductionmentioning

confidence: 97%

Evaluation of cytogenotoxicity, antioxidant and hypoglycemiant activities of isolate compounds from Mansoa hirsuta D.C. (Bignoniaceae)

Pereira

Queiroz

Siqueira

et al. 2017

An. Acad. Bras. Ciênc.

View full text Add to dashboard Cite

Mansoa hirsuta (Bignoniaceae) is a native plant from caatinga in Brazilian semiarid. This plant has been locally used as antimicrobial and hypoglycemiant agents, but their action mechanisms and toxicity remain largely unknown. Therefore, we evaluated the composition and antioxidant, cytoprotective and hypoglycemiant effects of raw extract, fractions and compounds from leaves of M. hirsuta. The cytogenotoxic effects of ursolic and oleanolic acids, the main phytotherapic components of this plant, were assessed. The raw extract and fractions presented steroids, saponins, flavonols, flavanonols, flavanones, xanthones, phenols, tannins, anthocyanins, anthocyanidins and flavonoids. The ethyl acetate fraction inhibited efficiently the cascade of lipid peroxidation while the hydroalcoholic fraction was richer in total phenols and more efficient in capturing 2,2-diphenyl-1-picrylhydrazyl ( · DPPH) and 2,2'-azinobis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS ·+ ) radicals. The isolated fraction of M. hirsuta also inhibited the α-amylase activity. Cytotoxic effects were absent in both raw extract and fractions while ursolic+oleanolic acids were efficient in protecting cells after exposure to hydrogen peroxide. Moreover, this mixture of acid shad no significant interference on the mitotic index and frequency of nuclear and/ or chromosomal abnormalities in Allium cepa test. Therefore, M. hirsuta represents a potential source of phytochemicals against inflammatory and oxidative pathologies, including diabetes.

show abstract

Section: Introductionmentioning

confidence: 97%

Evaluation of cytogenotoxicity, antioxidant and hypoglycemiant activities of isolate compounds from Mansoa hirsuta D.C. (Bignoniaceae)

Pereira

Queiroz

Siqueira

et al. 2017

An. Acad. Bras. Ciênc.

View full text Add to dashboard Cite

show abstract

“…Species of this type provide wood to make fences; construct lobster traps or for other uses requiring a wood of great durability due to their high decay resistance. It is also used as fire wood due to the high content of essential oil that may vary from 0.5% to 1.5%, the leaves and barks are used as an infusion or simply chewed as a folk medicine for the treatment of gastrointestinal disturbances, rheumatism and headache (Mattos, 1999;Chaves and Reinhard, 2003). This plant is rich in clerodane and cleisthantane type diterpenes with diverse biological activity (McChesney et al, 1991).…”

Section: Introductionmentioning

confidence: 99%

Antinociceptive effect of leaf essential oil from Croton sonderianus in mice

et al. 2005

View full text Add to dashboard Cite

“…Con respecto a los estudios polínicos en coprolitos -copropalinología -, existen antecedentes realizados en heces fósiles de diferente origen zoológico: de humanos, llamas, bóvidos extinguidos, hienas, loros, perros, ovejas, entre otros (D´Antoni y Togo 1974a, 1974bJones y Bonavía 1992;Edwards et al 1995;Sutton y Reinhard 1995;Alcover et al 1999; Carrión et al 2001Carrión et al , 2004Carrión et al , 2005 Reinhard 2003Reinhard , 2006Horrocks et al 2003, Dean 2006, de Porras 2010.…”

Section: Antecedentesunclassified

Coprolitos De Camélidos Del Holoceno Como Indicadores Paleoambientales

et al. 2010

View full text Add to dashboard Cite

RESUMENEl estudio de coprolitos permite abordar aspectos ecológicos y culturales de poblaciones pasadas, como reconstrucciones del paleoambiente, de paleodietas, inferir estacionalidad en el uso de los recursos y situaciones de parasitismo. El objetivo de este trabajo es reconocer el aporte del análisis polínico de coprolitos para las reconstrucciones paleoambientales e identificar posibles ítems de la dieta de guanacos del Holoceno del área cercana al sitio Cerro Casa de Piedra 7 (Parque Nacional Perito Moreno, Santa Cruz, Argentina). Se analizó el contenido polínico de 15 coprolitos de guanaco provenientes de 7 capas arqueológicas entre 9.640 ± 190 y 5.400 ± 64 14 C años AP. La extracción polínica se llevó a cabo mediante acetólisis y se realizó la determinación y recuento bajo microscopio óptico. Se registró la presencia de tejido vegetal y de restos de parásitos. Se comparó el espectro polínico de los coprolitos con el espectro de los sedimentos y se realizaron análisis estadísticos. Los tipos polínicos dominantes fueron: Nothofagus, Empetrum rubrum, Asteraceae subfam. Asteroideae y Nassauvia, Poaceae y Caryophyllaceae. Los conjuntos polínicos de coprolitos y sedimentos contemporáneos presentan similitudes en algunos casos y diferencias en proporciones o en composición en otros. Las similitudes encontradas entre coprolitos y sedimentos permiten inferir que el polen de los coprolitos refleja los taxones dominantes de la vegetación, por el contrario cuando hay mayor abundancia de ciertos tipos polínicos en los coprolitos que en los sedimentos, podría deberse a que el polen de los coprolitos está sesgado con sobrerrepresentaciones de los ítems preferidos por el guanaco, mientras que si la abundancia es mayor en los sedimentos que en los coprolitos, podría deberse a que las plantas consumidas no estaban en su período de floración. Los resultados de este trabajo muestran el valor de los coprolitos como indicadores paleoambientales y aportan datos para la reconstrucción paleoambiental y de dieta de los guanacos.PALABRAS CLAVES: coprolitos, camélidos, paleoambiente, Patagonia, polen. ABSTRACTThe study of coprolites permits to deal with ecological and cultural aspects of past populations, such as palaeoenvironmental reconstructions, palaeodiets, inferences related to the use of resources and parasitism status. The objective of this work is the recognition of the contribution of studies of pollen in coprolites to the palaeoenvironmental reconstructions, and the identification of probable items in the diet of guanacos living during the Holocene in the area near the site Cerro Casa de Piedra 7 (Perito Moreno National Park, Santa Cruz, Argentina). The pollen content of 15 coprolites of guanacos coming from seven archaeological layers dated by 14 C and resulting in ages between 9.640 ± 190 years BP and 5.400 ± 64 years BP were analysed. Pollen extraction was performed through acetolysis, and determination and counting under optical microscope. The presence of plant tissue and parasite remains was recorded. The coprolite...

show abstract

Paleopharmacology and pollen: theory, method, and application

Cited by 34 publications

References 20 publications

Evaluation of cytogenotoxicity, antioxidant and hypoglycemiant activities of isolate compounds from Mansoa hirsuta D.C. (Bignoniaceae)

Evaluation of cytogenotoxicity, antioxidant and hypoglycemiant activities of isolate compounds from Mansoa hirsuta D.C. (Bignoniaceae)

Antinociceptive effect of leaf essential oil from Croton sonderianus in mice

Coprolitos De Camélidos Del Holoceno Como Indicadores Paleoambientales

Contact Info

Product

Resources

About