Paliperidone: another treatment option for delusional parasitosis

Altınöz, Ali Ercan; Altınöz, Şengül Tosun; Kucukkarapinar, Melike; Çoşar, Behçet

doi:10.1177/1039856214546390

Cited by 15 publications

(14 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Delusional infestation is a psychiatric condition classified in the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5) as a delusional disorder, somatic type . The delusion in these patients is that they mistakenly believe their skin or other body parts are infested by small, living organisms .…”

Section: Definitionmentioning

confidence: 99%

“…This can progress to create a range of skin irritation and damage in varying stages of healing. Additionally, patients might cause intentional damage to skin in attempts to expose organisms which they believe are lying beneath the surface of the skin . Visible skin damage is often more severe on the side opposite of the patient's dominant hand …”

Section: Clinical Featuresmentioning

confidence: 99%

“…These specimens have been known to contain a variety of things which are common in patients' immediate environment including string, lint, plant material, common insects like ants, and skin flakes Insomnia: Patients may also complain of insomnia secondary to their tactile symptomatology or secondary to their response to the delusion, for example, waking up to change undergarments multiple times in the night Isolation: Patients may isolate themselves from friends and family out of fear that they may contaminate others, become further infested, or out of embarrassment.…”

Section: Clinical Featuresmentioning

confidence: 99%

“…No antipsychotic treatment is specifically indicated for primary DI, but many have had favorable results in patients. Studies performed comparing responses of typical and atypical – or, first and second generation – antipsychotics determined that neither was superior to the other . Therefore, it is important to tailor a patient's antipsychotic therapy based on the side effect profile of each antipsychotic.…”

Section: Treatmentmentioning

confidence: 99%

“…Further information on effective dose ranges for patients with primary DI from prior case studies and reports is included below. ◦Atypical antipsychotics ▪ Amisulpride 200–400 mg/day ▪ Aripiprazole 2–30 mg/day ▪ Olanzapine 2.5–20 mg/day ▪ Paliperidone 6–12 mg/day One case responded to paliperidone following a failed attempt with pimozide Success with paliperidone in particular was found in multiple case studies.…”

Section: Treatmentmentioning

confidence: 99%

See 4 more Smart Citations

Delusional infestation: a prototype of psychodermatological disease

2019

View full text Add to dashboard Cite

Delusional infestation (DI) is a disorder in which patients express a firm, unwavering belief that they are infested with some type of organism but otherwise have a typical grasp on reality with relatively normal cognitive functioning. Although classified as a somatic delusional disorder, DI requires special consideration due to its complicated clinical presentation, requiring attention to several possible explanations for the symptoms the patients describe. The purpose of the current review is to first summarize the clinical background and features of the diagnosis then explore treatment options. DI is a rare disorder though has reported cases dating back to the 19th century and spanning across the globe. Patients often experience the disorder as secondary to a medical condition, including substance use/withdrawal. However, there have also been many reported cases of primary DI, occurring in the absence of any other psychiatric or medical disorder.Clinically, DI is a diagnosis of exclusion, where the physician must rule out other medical conditions, including genuine dermatological disorders or infestations, or contributions from medications or substances. Patients with the disorder more commonly present to nonpsychiatric healthcare providers, making it essential for all clinicians to be able to identify the disease. Treatment can include either first or second generation antipsychotics, but it is important to proceed tactfully in discourse with the patient, being careful to address patients in a straightforward manner without reinforcing or questioning the delusion and focusing conversation on what can be done for the symptoms. Future research can continue to evaluate pathophysiology underlying primary DI, which historically has been an under-studied topic.

show abstract

Section: Definitionmentioning

confidence: 99%

Section: Clinical Featuresmentioning

confidence: 99%