Palliative sedation at the end of life at a tertiary cancer center

Abstract

PS is an important intervention in the management of terminal disease by a consulting palliative care team. Improved collaboration and communication between the hospital staff and the PCCT should be offered to meet patients' needs when PS is required.

Determinants of the Administration of Continuous Palliative Sedation: A Systematic Review

“…14 A study by Caraceni and colleagues, published after April 2011, confirmed the result of Miccinesi and colleagues by showing that palliative sedation was more frequently indicated in male patients (odds ratio 3.2; 95% confidence interval 1.5-7.0). 15 In general, women have different trajectories at the end of life than men. Indeed, women tend to live longer and have a different disease epidemiology and are more likely to receive care in a nursing home at the end of life, which may lead to different medical end-of-life decisions.…”

“…4 The frequency of palliative sedation has been reported to range from 2.5% to 64% among terminally ill patients. 14,15 This wide range likely reflects variations in the definition of the term and differences in culture and clinical settings.…”

Palliative Sedation for Status Epilepticus in a Patient with Progressive Multifocal Leukoencephalopathy

“…In addition, the duration of PS may be unusually longer. In this case, PS lasted for 39 days, whereas it is found in the literature to reach an average of less than 5 days [6][7][8] .…”

In-service documentation tools and statements on palliative sedation in Germany—do they meet the EAPC framework recommendations? A qualitative document analysis

“…Misunderstandings concerning probable life-shortening effects of PS and differentiating PS from euthanasia (2)(3)(4) may have led to barriers and concerns in the application of PS in clinical practice. Rather inconsistent treatment regimens and research findings on the definition (1,(5)(6)(7)(8), incidence (9,10), indications (10)(11)(12), medication, and general professionals' attitudes (13)(14)(15)(16)(17)(18) toward PS were reported (9,15). Due to these uncertainties, the necessity for standardized guidelines was expressed (19).…”