Pancreatitis and myocarditis followed by pulmonary hemorrhage, a rare presentation of leptospirosis- A case report and literature survey

Ranawaka, Nuwan; Jeevagan, Vijayabala; Karunanayake, Panduka; Jayasinghe, Saroj

doi:10.1186/1471-2334-13-38

Cited by 22 publications

(27 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Pancreatitis is a described sequel to leptospirosis in human patients (Ranawaka et al . ). Pancreatitis can develop in dogs with acute leptospirosis and can explain the acute abdominal discomfort as well as anorexia and vomiting in dogs in which azotaemia and jaundice have resolved (Greene ).…”

Section: Clinical Findingsmentioning

confidence: 97%

European consensus statement on leptospirosis in dogs and cats

Schuller

Francey

Hartmann

et al. 2015

J of Small Animal Practice

242

377

View full text Add to dashboard Cite

Leptospirosis is a zoonotic disease with a worldwide distribution affecting most mammalian species. Clinical leptospirosis is common in dogs but appears to be rare in cats. Both dogs and cats, however, can shed leptospires in the urine. This is problematic as it can lead to exposure of humans. The control of leptospirosis, therefore, is important not only from an animal but also from a public health perspective. The aim of this consensus statement is to raise awareness of leptospirosis and to outline the current knowledge on the epidemiology, clinical features, diagnostic tools, prevention and treatment measures relevant to canine and feline leptospirosis in Europe.

show abstract

Section: Clinical Findingsmentioning

confidence: 97%

European consensus statement on leptospirosis in dogs and cats

Schuller

Francey

Hartmann

et al. 2015

J of Small Animal Practice

242

377

View full text Add to dashboard Cite

show abstract

“…Leptospirosis-mediated myocarditis is an uncommon disease even in human medicine, it is rarely defined and most data are known from endemic regions (Kularatne et al, 2011;Navinan and Rajapakse, 2012;Panagopoulos et al, 2014;Rajiv et al, 1996;Ranawaka et al, 2013;Shah et al, 2010;Turhan et al, 2008). In veterinary literature, there is a lack of data of myocardial involvement in leptospirosis patients (Loftis et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

Immun?-Mediated Myocarditis Associated with Leptospirosis in 6 Years Old Labrador Retriever

Dmitrii¹,

Anna

2018

American Journal of Animal and Veterinary Sciences

View full text Add to dashboard Cite

About 6 years old, male Labrador retriever was presented for 10 days long weakness and fatigue. After diagnostic examinations, a preliminary diagnosis of Leptospirosis was suggested. Cardiologist consultation was advised. At admission, the dog was depressed, the visible mucosa was pale and capillary refilling time was slowed. Weak systolic murmur and rhythm disturbances were auscultated. Thoracic radiography revealed the accented bronchial pattern and non-significant peribronchial opacity. Cardiac silhouette stayed within normal limits. Two-dimensional echocardiography showed mild hypertrophy of left ventricular walls, with wall segments hypokinesia. The chambers were not dilated, there was no evidence of valves damage. Systolic function was preserved. Electrocardiography showed several sinus complexes and paroxysms of ventricular tachycardia up to 30-40 beats. Myocarditis was suspected and Bartonellosis (Bart. vinsonii&henselae), Borreliosis (Bor. burgdorferi), Troponin I tests were recommended. Amiodarone, ramipril, doxycycline, ampicillin and prednisone were prescribed and an endomyocardial biopsy was performed. Histopathological examination revealed severe myocardial degeneration and inflammatory cells infiltration. Based on positive tissue PCR Leptospirosis test and histopathology findings, excluding other possible infection, resulting in myocardium inflammation, the diagnosis of immune-mediated secondary myocarditis was made.

show abstract

“…In Sri Lanka, pancreatitis was previously reported in one confirmed [10] and one probable [11] cases of leptospirosis.…”

Section: Discussionmentioning

confidence: 99%

Severe leptospirosis and pancreatitis; A case series from a leptospirosis outbreak in Anuradhapura district, Sri Lanka

2016

View full text Add to dashboard Cite

BackgroundAcute pancreatitis is identified as an atypical and rare presentation of leptospirosis. In this report, we discuss a case series of severe leptospirosis with pancreatitis as a main complication during an unusual outbreak of leptospirosis in Anuradhapura district, Sri Lanka.Case presentationWe retrospectively reviewed clinical presentation, investigations, treatment and outcome of six confirmed cases of severe leptospirosis admitted to intensive care unit (ICU) of Teaching Hospital, Anuradhapura, within a three months period from November 2014 to January 2015.All six patients were previously healthy paddy farmers presented with fever, myalgia and arthralgia. Four patients had abdominal pain, nausea and vomiting on admission. Hypotension, Neutrophilic leukocytosis and thrombocytopaenia was detected in all patients in the initial stage. Four patients had serum amylase more than 900 (range 941–2420). All patients had acute kidney injury and hepatitis. Significantly elevated amylase and low serum calcium were present in 4 cases. Five patients recovered without any evidence of residual organ damage, but one succumbed to the illness.ConclusionThis case series emphasizes the importance of identification of acute pancreatitis as a common complication of Leptospirosis, in order to reduce mortality and morbidity.

show abstract

Pancreatitis and myocarditis followed by pulmonary hemorrhage, a rare presentation of leptospirosis- A case report and literature survey

Cited by 22 publications

References 23 publications

European consensus statement on leptospirosis in dogs and cats

European consensus statement on leptospirosis in dogs and cats

Immun?-Mediated Myocarditis Associated with Leptospirosis in 6 Years Old Labrador Retriever

Severe leptospirosis and pancreatitis; A case series from a leptospirosis outbreak in Anuradhapura district, Sri Lanka

Contact Info

Product

Resources

About