Pandemic of Fear or What Statistics Hide: Patients with Cardiovascular Disease are at Increased Risk During COVID-19

Gaisenok, O. V.

doi:10.17987/icfj.v21i0.711

Cited by 2 publications

(2 citation statements)

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“…Current evidence suggests fear of the epidemics and pandemics may cause various health concerns (de Paiva Teixeira et al., 2020; Gaisenok, 2021; Ornell et al., 2020; Wessler et al., 2020). Such fears can impact increased mortality and morbidity along with the associated increased incidence of heart disease or diabetes (Pouwer et al., 2010; Wessler et al., 2020).…”

Section: Discussionmentioning

confidence: 99%

Health literacy and fear among Iranian medical students due to COVID‐19: An observational study

et al. 2022

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Introduction The coronavirus disease of the 2019 (COVID‐19) pandemic has created a sense of fear due to uncertainties in medical students’ personal and professional lives. Medical education is challenging and poses a more significant academic and emotional rigor when compared with other professional programs. With the COVID‐19 having limited treatment options, health literacy (HL) is crucial for managing and responding to the pandemic. This research aims to examine the impact of HL on COVID‐19‐associated fear among Iranian medical students. Methods A cross‐sectional study was conducted measuring the HL and fear of COVID‐19 using validated scales. Two hundred and seventy‐eight survey responses were received and analyzed descriptively by using SPSS software inferential statistics. Results Mean age of participants was 22.93 ± 5.427 years. The correlation between students’ total health literacy (HELIA) scores and their fear of COVID‐19 (FCV‐19S) scores was −0.279 (p value = .019). The FCV‐19S has a negative correlation with total HELIA in the group of females and males, single and married people, bachelor and MD students, and students living in rural areas and urban areas. The negative correlation of FCV‐19S with total HELIA in males and students who reside in rural areas was the only one that was not significant. In associate degree students, the correlation between FCV‐19S and total HELIA was positive but not significant. Education grades had a significant impact on FCV‐19S. Furthermore, the place of residence also had a significant impact on FCV‐19S. However, the gender and marital status did not significantly impact FCV‐19S. Conclusions The present study showed that students with higher HL scores had lesser fear of COVID‐19. The key stakeholders require several positive strategies to reduce fear and improve health, and such vital policies will assist in improving the students’ health and achieving the sustainable developmental goals.

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Section: Discussionmentioning

confidence: 99%

Health literacy and fear among Iranian medical students due to COVID‐19: An observational study

et al. 2022

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“…Обсуждение данного клинического случая, безусловно, можно рассматривать как дискуссионную проблему безопасности и эффективности проводимой терапии у такой пациентки. Пациенты с сердечно-сосудистыми заболеваниями оказались наиболее подвержены риску различных осложнений в период пандемии COVID-19 [34]. Пациентка пожилого возраста, вероятно, первоначально получила острое повреждение почек в рамках контраст-индуцированной нефропатии во время первичного ЧКВ в первом стационаре, которое разрешилось самостоятельно.…”

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The Problem of Drug Interactions Between Rosuvastatin and Ticagrelor in the Aspect of the Risk of Rhabdomyolysis: Discussion of the Problem and Description of the Clinical Case

Gaisenok¹,

Chichkov²,

Леонова³

2022

Racionalʹnaâ farmakoterapiâ v kardiologii

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Background. Combination therapy with two antiplatelet agents (ticagrelor or clopidogrel plus acetylsalicylic acid) and a high dose statin is recommended in accordance with clinical guidelines for patients undergoing acute coronary syndrome and coronary intervention. Combined therapeutic regimens have drug-drug interaction potential. Rhabdomyolysis is a known side effect of statin therapy, and there is evidence that co-therapy with ticagrelor increases the risk of this complication.Case description. A 72-year-old female patient was hospitalized with typical signs of rhabdomyolysis: muscle pain, oliguria, weakness, significant increases in creatine kinase (CK), myoglobin and creatinine. One month before that, she was urgently hospitalized with acute recurrent ST-elevation myocardial infarction and underwent endovascular intervention on a critical stenosis of the left anterior descending artery with stent implantation. After that, rosuvastatin 40 mg per day and ticagrelor 90mg 2 times a day were added to her therapy. During the current hospitalization, rosuvastatin, ACE inhibitors and spirolactone were canceled, infusion therapy was carried out, which led to a rapid regression of symptoms, restoration of adequate diuresis, and normalization of CK, myoglobin and creatinine levels. Conclusions. The combined use of ticagrelor with rosuvastatin (especially at a high dose) increases the risk of rhabdomyolysis in elderly patients. Patients taking ticagrelor may require changes in statin therapy, dose adjustments, and possible drug changes to avoid pharmacological interactions and an increased risk of side effects.

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Pandemic of Fear or What Statistics Hide: Patients with Cardiovascular Disease are at Increased Risk During COVID-19

Cited by 2 publications

References 21 publications

Health literacy and fear among Iranian medical students due to COVID‐19: An observational study

Health literacy and fear among Iranian medical students due to COVID‐19: An observational study

The Problem of Drug Interactions Between Rosuvastatin and Ticagrelor in the Aspect of the Risk of Rhabdomyolysis: Discussion of the Problem and Description of the Clinical Case

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