Panhipopituitarismo congénito como parte del síndrome de incisivo único medial

Ogando, A. Rodríguez; Martín, M.B. Roldán; Arnao, M.D. Rodríguez; Sánchez, Ana Rodríguez

doi:10.1016/j.anpedi.2010.09.027

Cited by 3 publications

(2 citation statements)

References 11 publications

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“…However, since deficiency of growth hormone is not a thanatophoric condition, the patient may reach adulthood, although he/she will be marked by the characteristics acquired in childhood, such as height below 120 cm, which is the maximum attainable. The poor development of the forehead may lead to the maxilla and mandible being abnormally small, so that the physiological changes associated with tooth eruption may lead to tooth malformation [5–7]. …”

Section: Introductionmentioning

confidence: 99%

Dental Abnormalities in Pituitary Dwarfism: A Case Report and Review of the Literature

Ferrante

Blasi

Crippa

et al. 2017

Case Reports in Dentistry

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Hypopituitarism is a disorder caused by a reduced level of trophic hormones that may be consequent on different destructive processes. The clinical manifestations depend on the type of hormone involved. A deficiency of growth hormone (GH) in children causes the lack of growth known as pituitary dwarfism. The case is reported of a patient with pituitary dwarfism, multiple dental anomalies, functional prosthetic problems, and a revision of the literature. She was subjected to prosthetic rehabilitation without surgical intervention, using zirconium substructures, thus eliminating the potential complications that may require trauma surgery. The therapeutic approach adopted led to excellent results and restored an aesthetic smile.

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Section: Introductionmentioning

confidence: 99%

Dental Abnormalities in Pituitary Dwarfism: A Case Report and Review of the Literature

Ferrante

Blasi

Crippa

et al. 2017

Case Reports in Dentistry

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“…Esta entidad presenta una incidencia de 0,5/100.000 nacidos vivos (1); solo el 23% de los casos se diagnostica en el periodo neonatal, lo cual implica un incremento en las complicaciones posnatales hasta del 52% (2). Se define como un trastorno de la conexión entre la pituitaria y el hipotálamo, capaz de conducir anatómicamente a una hipogenesia de la pituitaria anterior y agenesia o ectopia de la hipófisis posterior.…”

Section: Introductionunclassified

Panhipopituitarismo congénito secundario a interrupción del tallo hipofisario: informe de caso

Agudelo

Maldonado

Tovar

et al. 2015

Rev. Colomb. Enferm.

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RESUMENLa disrupción del tallo hipofisario es una patología infrecuente que causa hipogenesia de la pituitaria anterior y agenesia o ectopia de la hipófisis posterior. El diagnóstico se realiza tardíamente cuando aparecen mayores alteraciones antropométricas o disminuciones en la velocidad de crecimiento. Se estima que solo el 23% de los casos se diagnostica en el periodo neonatal, con lo cual se logra disminuir la mortalidad y morbilidades secundarias. Este estudio describe el caso de un recién nacido con hipoglicemia persistente desde el nacimiento, micropene e incisivo único central. Se solicitó resonancia magnética cerebral y determinación sérica hormonal para confirmar el diagnóstico de panhipopituitarismo congénito secundario a la disrupción del tallo hipofisario. Se inició el reemplazo hormonal de forma temprana.Palabras clave: hipopituitarismo, adenohipófisis, hormona del crecimiento, recién nacido, hipoglicemia.

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Developmental enamel defects and dental anomalies of number and size in children with growth hormone deficiency

Torlińska-Walkowiak,

Majewska,

Sowińska

et al. 2023

Sci Rep

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Growth hormone is meaningfully involved in the processes of tooth cells differentiation and tissue formation. The aim of the study was to evaluate the occurrence of dental anomalies: microdontia, macrodontia, hypodontia and developmental defects of enamel (DDE) amongst a group of isolated growth hormone deficient (GHD) patients and healthy children. This cross-sectional study was based on a group of 101 Caucasian children: 33 with GHD (mean age 10.94, SD 2.51) and 68 being healthy, normal height subjects (mean age 10.4, SD 2.38). The dental examination in primary and permanent teeth was carried out by one trained and calibrated dentist, in accordance with the WHO guidelines. It was observed that 33% of GHD patients suffer from dental anomalies (hypodontia, microdontia or macrodontia), the difference between the study group and the control group was statistically significant (33% vs 4%, p < 0.001). Hypodontia and microdontia/macrodontia were the most common problems affecting 18% and 21% of the GHD individuals, respectively. The prevalence of DDE did not differ significantly between GHD group and the control group (58% vs 48%, p > 0.05). As children with GHD present more dental anomalies than their healthy coevals, clinicians should be aware of the possible oral health problems associated with GHD and consider dental screening and management as part of the patient’s overall health care plan.

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Panhipopituitarismo congénito como parte del síndrome de incisivo único medial

Cited by 3 publications

References 11 publications

Dental Abnormalities in Pituitary Dwarfism: A Case Report and Review of the Literature

Dental Abnormalities in Pituitary Dwarfism: A Case Report and Review of the Literature

Panhipopituitarismo congénito secundario a interrupción del tallo hipofisario: informe de caso

Developmental enamel defects and dental anomalies of number and size in children with growth hormone deficiency

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