Papaya Latex for Healing the Second Degree of Burn Wound in Male Mice

Surya, Kuning Eny; Khu, Adrian; Raif, Ahmad; Ikhtiari, Refi

doi:10.1109/inhence52833.2021.9537269

Cited by 1 publication

(1 citation statement)

References 36 publications

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“…Another study also reported that temulawak extract could accelerate wound closure in white rats by 15,262% per-day compared to the group that was not treated 20 . Pieces of literature reveal that the treatment with antioxidants strengthens cellular antioxidant defense mechanisms, can reduce free radicalmediated damage and minimize tissue damage during burn injury, and can accelerate the wound healing process 21,22 .…”

Section: Resultsmentioning

confidence: 99%

Effectiveness of temulawak (Curcuma xanthorrhiza) ointments as wound healing agents in wistar rats

Panjaitan

Girsang

Chiuman

2022

J. Teknol. Laboratorium

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Temulawak is known for its potential as a powerful antioxidant, anti-inflammatory, and anti-aging. Numerous studies have been reported on how temulawak extract components minimize wrinkles, boost collagen production, and prevent degradation. This study aims to determine whether temulawak extract promotes wound healing in Wistar rats. Pure experimental laboratory research and only post-test control group design observations have been done. Our results showed changes in the macroscopic appearance of wounds, particularly in the look of closed, dry wounds, which were exclusively observed in patients who received ointments containing 15%, 20% and 25% temulawak extract after 14 days. Based on the histopathology observation there was a significant difference in the mean comparison of the area of epithelialization, the number of fibroblasts, and the quantity of angiogenesis. We conclude that temulawak extract benefited incision wound healing in Wistar rats.

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Section: Resultsmentioning

confidence: 99%