Paper-based Chemiluminescence Device with Co-Fe Nanocubes for Sensitive Detection of Caffeic Acid

Abstract

In this work, a new chemiluminescence (CL) system of Co-Fe prussian blue analogs nanocubes (Co-Fe PBA NCs) which can catalyze luminol to produce strong CL in the absence of H2O2 was established. Co-Fe PBA NCs has the property of oxidase-like activity and it can catalyze the generation of active oxygen radicals in the dissolved oxygen system. Since caffeic acid (CA) can remove reactive oxygen species in the system, a sensitive detection method for CA on the paper-based chip was developed.Under the optimal conditions, the method showed good linear response to CA in the range of 10 ng/mL-800 ng/mL with the limit of 3 ng/mL. The proposed method had been used for the determination of CA in tea samples. The results may open a new avenue for the catalytic property on luminol CL system without extra oxidants.

Investigating the oxidase-like activity of a Co–Fe Prussian blue analogue nanocube prepared in situ and its applications in the colorimetric detection of ascorbic acid, alkaline phosphatase, α-glucosidase, and ascorbic acid oxidase

“…22 The bands at 2118 cm −1 and 2029 cm −1 are related to the Co( ii )–NC–Fe( iii ) and Co( ii )–NC–Fe( ii ) species, respectively, signifying the nature of the CN bond in the molecule. 23,24 The morphology was studied by SEM and TEM. In the SEM image shown in Fig.…”

“…S2 (ESI†) that compared with the blank group, the absorbance at 652 nm decreases successively with the increase in IPA, SOD or histidine concentration, suggesting that O 2 ˙ − , ˙OH, and 1 O 2 are active intermediate species during the catalytic process, which is consistent with the previous report. 24…”

Recent Advances and Applications in Paper-Based Devices for Point-of-Care Testing

“…The dual mode detection (FL and CL) was achieved with the LODs of 0.3 ng/mL for CL and 0.2 ng/mL for FL. In 2021, it was reported that by using Co-Fe Prussian blue analogue nanocubes (Co-Fe PBA NCs), the strong CL still happened in the absence of H 2 O 2 on a paper-based CL device [ 286 ].…”

Nanoparticles Based on Prussian Blue for Biosensor Applications: A Review

“…(B) Determination of caffeic acid in tea samples by a CoFePBA-based chemiluminescence system. Reprinted with permission from ref . Copyright 2020, The Japan Society for Analytical Chemistry.…”