Paper-Based Sensors for Biomedical Applications

Paper-Based Cell Culture: Paving the Pathway for Liver Tissue Model Development on a Cellulose Paper Chip

“…The intrinsic wicking and capillary nature of these matrices also facilitate integration with the fluidic systems. , The paper substrates are eco-friendly, cost-effective, portable, easy to modify (chemically or physically) and have large-scale availability, , and consequently they have been implemented in various aspects of biomedical engineering ( e.g. , the development of healthcare diagnostic tools, paper-based biosensors, paper-based flexible electronic devices, and even as cell culture platforms). − The present review systematically delineates the prospects of employing a paper matrix for reconstruction of the liver models.…”

Paper-based chemometer device for the estimation of α-amylase—a biomarker for pancreatitis

“…Similar results have also been observed in previous studies. 13,47 This shows that the pores were all filled with the melted toner material. Magnification was taken 100 times with a 100 μm size of the view, and the size of the pores was approximately 23.5 μm when measured with Image J software (Grade 4 Whatman filter paper usually has a pore size of 20–25 μm).…”

“…Some of them include wax printing, screen printing, photolithography, laser cutting, three-dimensional printing, etc. [12][13][14] These fabrication techniques make the paper an alternative for making cheaper lab-on-chip devices for analysis purposes in the food and beverage industries and diagnostic purposes in the medical sector. 15,16 The use of paper-based materials also makes these devices environmentally friendly and easily disposable.…”

Modular and Substrate-Independent Grafting-To Procedure for Functional Polymer Coatings

“…To illustrate the scope of the grafting-to procedure presented in this study, three substrate types with widely varying chemical characteristics were selected as target substrates: gold (as, e.g., relevant for biomedical applications like surface plasmon resonance (SPR) sensing. − ), silicon with a native silicon oxide layer (SiO 2 ) (given its use in biomedical applications and photovoltaics , ), and polymer-coated glass (PE), to demonstrate that the procedure can be applied to polymeric substrates, which are generally difficult to efficiently functionalize . To further illustrate the modularity of the procedure, five different block copolymers were synthesized via radical addition-fragmentation chain-transfer (RAFT) polymerization, all of which contained a short poly­(glycidyl methacrylate) (poly­(GMA)) segment that was incorporated to bind to the amine groups present in the poly­(dopamine) film.…”