Papillary carcinoma of thyroid in a 11 months old child

Poddar, Soumita; Basu, Siddhartha; Majumder, Anup; Devleena,

doi:10.4103/0971-5851.51430

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…9 Although causes for the development of papillary thyroid carcinoma are not completely clear, radiation exposure is proven to be one of the major known risk factors, with the RET/PTC or P53 mutations being the most common genetic alterations associated with radiationinduced papillary thyroid carcinoma. 5,6,[13][14][15] The average latency period from radiation exposure to malignancy ranges from 7 to 30 years. 6,13 It is well known that genetic factors play an important role in the development of malignancy.…”

Section: Discussionmentioning

confidence: 99%

“…5,6,[13][14][15] The average latency period from radiation exposure to malignancy ranges from 7 to 30 years. 6,13 It is well known that genetic factors play an important role in the development of malignancy. In thyroid malignancies, approximately 5% of cases involve familial nonmedullary thyroid carcinoma, which include cases with 2 or more family members diagnosed with nonmedullary thyroid cancer.…”

Section: Discussionmentioning

confidence: 99%

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Thyroid Papillary Carcinoma in a 3-year-old American Boy with a Family History of Thyroid Cancer

Khara

Silverman²,

Bethel³

et al. 2010

Journal of Pediatric Hematology/Oncology

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Differentiated thyroid carcinoma is a rare malignancy in children. It represents 0.4% to 3.0% of all childhood malignancies, with greater than 70% of cases presenting between the ages of 11 to 17 years and is exceptionally rare in children under 5 years of age. The most common type of differentiated thyroid carcinoma in children is papillary thyroid carcinoma, most of which are believed to be related to radiation exposure and only approximately 5% of cases have a family history of papillary thyroid cancer. In this report, we present a papillary thyroid carcinoma in a 3-year-old American boy with a family history of thyroid cancer and no known history of radiation exposure. A literature review with discussion on the management and treatment of pediatric papillary thyroid carcinoma follows.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Thyroid Papillary Carcinoma in a 3-year-old American Boy with a Family History of Thyroid Cancer

Khara

Silverman²,

Bethel³

et al. 2010

Journal of Pediatric Hematology/Oncology

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Papillary thyroid carcinoma in an 8-year-old Ethiopian child: A case report with literature review

Tirkaso,

Mulugeta,

Belete

et al. 2024

SAGE Open Medical Case Reports

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Thyroid nodular disease can present in different forms, such as a solitary nodule, multinodular goiter, nodular goiter caused by autoimmune goiter, and nonpalpable thyroid nodules. Among children, thyroid cancer is the most common type of endocrine cancer. Pediatric thyroid cancer is usually detected as a neck mass without any symptoms, leading to variable stages of progression when diagnosed. Papillary thyroid carcinoma is the most common type of thyroid cancer in children with thyroid nodules. We are presenting a case of an 8-year-old male child who was referred to Jimma Medical Center after he developed swelling on the right side of his neck. On examination, multiple, matted 8 × 6 cm, firm to hard, non-tender right lateral neck masses were found, which moved with swallowing. Thyroid function tests were normal. An ultrasound diagnosis of thyroid carcinoma and a cytologic diagnosis of suspicion for papillary thyroid carcinoma (Bethesda V) was made, and an excisional biopsy was advised. A total thyroidectomy was done. A histopathology diagnosis of Papillary thyroid carcinoma (Classic variant) was made. This is an unusual case of Papillary thyroid carcinoma in an Ethiopian child, with plenty of examples previously recorded in the literature but no such report of its occurrence in our setup to our knowledge. When children under 10 have cervical masses, thyroid cancer should be considered. The evaluation of a palpable thyroid mass typically begins with a blood test to check thyroid function, along with ultrasound and fine-needle aspiration biopsy. Currently, fine-needle aspiration biopsy is the most reliable way to diagnose malignancy and determine the appropriate surgical approach. In most cases, treatment will involve a total thyroidectomy. Lymph node dissection is necessary only if lymph node disease is detected during preoperative evaluation.

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The first case of papillary thyroid carcinoma in an adolescent with congenital dyshormonogenetic hypothyroidism in Serbia

et al. 2014

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Papillary carcinoma of thyroid in a 11 months old child

Cited by 4 publications

References 6 publications

Thyroid Papillary Carcinoma in a 3-year-old American Boy with a Family History of Thyroid Cancer

Thyroid Papillary Carcinoma in a 3-year-old American Boy with a Family History of Thyroid Cancer

Papillary thyroid carcinoma in an 8-year-old Ethiopian child: A case report with literature review

The first case of papillary thyroid carcinoma in an adolescent with congenital dyshormonogenetic hypothyroidism in Serbia

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