Papillary Tumor of the Pineal Region in Children: Presentation of a Case and Comprehensive Literature Review

Choque-Velasquez, Joham; Colasanti, Roberto; Resendiz-Nieves, Julio; Jahromi, Behnam Rezai; Tynninen, Olli; Collan, Juhani; Niemelä, Mika; Hernesniemi, Juha

doi:10.1016/j.wneu.2018.06.020

Cited by 17 publications

(9 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Tumors in the pineal region are difficult to operate because of the complex adjacent relationship, important anatomical structure, and deep location. With the development of anesthesiology and imaging, especially the advent of CT and MRI, and the popularization of neurosurgery, direct surgical resection of lesions in this area has become possible, and the mortality rate has decreased significantly [ 9 ]. Therefore, the tumor at this site should be surgically removed as directly as possible, and precise neurosurgery and the selection of the best surgical approach are the keys to successful surgery [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

Clinical Efficacy of Endoscopic Infratentorial Supracerebellar Approach for Pineal Region Tumors: A Retrospective Case‐Control Study

Zhu

Xiong

Zhang

et al. 2022

Contrast Media & Molecular Imaging

View full text Add to dashboard Cite

Tumors in the pineal region are deep, with complex surrounding anatomy, adjacent to important blood vessels and nerve structures, and surgical resection is difficult and risky. In this paper, we reviewed the literature to understand the epidemiology and clinical manifestations of pineal region tumors in the country and study the clinical indications, related problems, and successful experiences of patients with pineal region tumors treated by the transtentorial-superior approach. The clinical data of 80 patients with pineal region tumors were selected as the retrospective research objects and divided into the control group and the treatment group, with 40 cases in each group, according to the random number table method. The control group was treated using the endoscopic transtentorial approach (Poppen approach), while the treatment group was treated with the endoscopic supratentorial approach (Krause approach). The inflammatory factors, inflammatory stress response, postoperative neurological dysfunction, clinical efficacy, and poor prognosis were observed and compared between the two groups. Tumor resection and recurrence were used to compare the clinical outcomes of tumors in the pineal region. The extent of surgical resection was 100% higher in both groups, and the treatment group was comparable to the control group. The prognosis of patients after the operation was poor. Nausea and vomiting, visual disturbance, upper vision paralysis, and ataxia in the treatment group were significantly lower than those in the control group, with no statistical significance (P > 0.05). At the same time, the bone window can be reduced to reduce trauma and provide a certain reference for patients to choose a safe and complete resection method.

show abstract

Section: Discussionmentioning

confidence: 99%

Clinical Efficacy of Endoscopic Infratentorial Supracerebellar Approach for Pineal Region Tumors: A Retrospective Case‐Control Study

Zhu

Xiong

Zhang

et al. 2022

Contrast Media & Molecular Imaging

View full text Add to dashboard Cite

show abstract

“…Positioning and draping the patient are procedures made under the previously well-described protocol developed in Helsinki for a more ergonomic variant of the classic sitting position, the sitting praying position. [1][2][3][4][5] The supracerebellar infratentorial (SCIT) approach, which is suitable for infratentorial lesions behind and below the neurovascular structures, is the most frequently used route for pineal region surgery at our institution. Along the years a modified paramedian approach to the pineal region was perfected and performed routinely due to complications observed with the classic midline approach.…”

Section: Pre-microsurgical Stagementioning

confidence: 99%

“…This approach is the second most frequently used at our institution and was widely described in another manuscripts. 4,5 The transcortical, and the subtemporal approach are less frequently performed for lesions extended laterally to the temporo-occipital gyri. Other approaches might be also used according to specific locations of recurrent or residual tumors.…”

Section: Pre-microsurgical Stagementioning

confidence: 99%

“…The pineal region or the so called posterior incisural space/quadrigeminal cistern is a deep intracranial structure that may harbor a big variety of neurosurgical diseases such as benign pineal cysts, a wide range of pineal region tumors, vascular malformations, and aneurysms. [1][2][3][4][5][6][7] The pineal region represents a microsurgical challenging location. Since the introduction of the operative microscope and, later, of the endoscope, the surgical outcome of these pathologies improved dramatically.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Extent of Resection and Long-Term Survival of Pineal Region Tumors in Helsinki Neurosurgery

et al. 2019

Self Cite

View full text Add to dashboard Cite

Background: Pineal region tumors represent challenging surgical lesions with wide ranges of survival rates reported in different surgical series. Here, we emphasize the role of the complete microsurgical resection (CMR) in order to obtain a favorable long-term outcome of pineal region tumors. Methods:We report a retrospective study of pineal region tumors operated in Helsinki Neurosurgery between 1997 and 2015. Information was obtained from the hospital records, and an evaluation of the Finnish population register was conducted in July 2018 to determine the current status of the patients.Results; 76 pineal region tumors were operated. The survival rate was 62 % at a mean follow up of 125±105 (0-588) months, and the disease-related mortality was limited to 14 (18.4%) patients. Up to July 2018, twenty-nine patients had died. 2 patients died 1 and 3 months after surgery with delayed thalamic infarctions, 12 patients with disease progression, and 15 had non disease-related deaths. Only one patient was lost in the long-term FU. 10/14 disease-related deaths occurred during the first 5 years of follow up: 5 diffuse gliomas, 3 germ cell tumors, 1 Grade II-III PPTID, and 1 meningioma. CMR was linked to better tumor free survival and long-term survival rates with exception of diffuse gliomas. Conclusion:CMR, in the setting of a multidisciplinary management of pineal region tumors, correlates with favorable survival rates and with minimal mortality. Surgically treated grade II-IV gliomas conform a particular group with high mortality within the first 5 years independently of the microsurgical resection.

show abstract

“…[9,11] Since it is first description in 2003 (Jouvet et al) and inclusion in the 2007 World Health Organization (WHO) classification of tumors of the nervous system, several pediatric cases of the PTPR were described up to date. [2,4,6,21,27] PTPR affects mostly young adults in the third decade of life. [14] Children account for only 16-19% of PTPR cases.…”

Section: Introductionmentioning

confidence: 99%

Papillary tumor of the pineal region in pediatric patient – A case report

Nemir

Marić

Trbojevic³

et al. 2022

Surgical Neurology International

View full text Add to dashboard Cite

Background: Papillary tumor of the pineal region (PTPR) represents a rare and histologically distinct subgroup of tumors originating in the pineal region. Few pediatric cases have been reported so far in the literature; therefore, clinical data are scarce. Case Description: We describe a case of PTPR in a 9-year-old girl who presented with a 5-month history of excessive appetite and weight gain. The patient underwent neuroimaging procedures and total gross surgical resection with postoperative adjuvant local radiotherapy, which from our experience was the best treatment choice as an attempt to avoid local recurrence. During 78-month follow-up, the patient from our study manifested no disease recurrence. Conclusion: PTPR should be included in the differential diagnosis of pineal region masses.

show abstract

Papillary Tumor of the Pineal Region in Children: Presentation of a Case and Comprehensive Literature Review

Cited by 17 publications

References 44 publications

Clinical Efficacy of Endoscopic Infratentorial Supracerebellar Approach for Pineal Region Tumors: A Retrospective Case‐Control Study

Clinical Efficacy of Endoscopic Infratentorial Supracerebellar Approach for Pineal Region Tumors: A Retrospective Case‐Control Study

Extent of Resection and Long-Term Survival of Pineal Region Tumors in Helsinki Neurosurgery

Papillary tumor of the pineal region in pediatric patient – A case report

Contact Info

Product

Resources

About