Papilomavírus humano e neoplasia cervical

Rosa, Maria Inês da; Medeiros, Lídia Rosi; Rosa, Daniela Dornelles; Bozzeti, Mary Clarisse; Silva, Fábio Rosa; Silva, Bruno Rosa

doi:10.1590/s0102-311x2009000500002

Cited by 45 publications

(50 citation statements)

References 99 publications

(107 reference statements)

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“…Em mulheres jovens, a infecção por HPV pode apresentar-se temporária, ocorrendo regressão sem que haja necessidade de tratamento (3)(4) . Entretanto, a manifestação Aproximadamente, 70% dos cânceres do colo uterino têm como etiologia os vírus HPV16 e HPV18 (3) , sendo o subtipo HPV16 o que demonstra risco elevado (1)(2) . outras doenças sexualmente transmissíveis (3) .…”

Section: Introductionunclassified

“…O câncer do colo uterino apresenta um dos mais altos potenciais de prevenção e cura, dentre os demais tipos de câncer, podendo ser diagnosticado na fase pré-clinica, a partir de medidas eficazes de rastreamento. É de grande importância a avaliação das lesões provocadas pelo HPV, pois quanto mais graves, mais aumentam as probabilidades de evoluírem para diagnóstico de câncer do colo uterino (3) .…”

Section: Introductionunclassified

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Rastreamento do câncer do colo do útero na região ampliada oeste de Minas Gerais

Rodrigues

Moreira

Alves

et al. 2016

R. Enferm. Cent. O. Min.

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Objetivo: analisar os indicadores do rastreamento do câncer do colo do útero na Região Ampliada Oeste de Minas Gerais, no período de 2007 a 2013. Método: trata-se de um estudo epidemiológico descritivo, com análise ecológica. Utilizou-se dados disponíveis no Sistema de Informação do Câncer de Colo do Útero de 54 municípios. A população elegível foram mulheres, usuárias do Sistema Único de Saúde, com idade entre 25 e 64 anos, que realizaram o exame Papanicolaou. A tabulação e a análise descritiva dos dados foram realizadas no software Statistical Package for the Social Sciences 20.0. Aprovado no comitê de ética pelo parecer número 718.783. Resultados: a cobertura de exames variou de 61,0% a 74,0%. A maioria tinha entre 35 e 54 anos. Foram consideradas insatisfatórias 0,86% das lâminas analisadas. O epitélio escamoso foi o mais evidenciado (99,1%) nas amostras. Observou-se a presença de inflamação em 41,9% dos exames. Prevalência de células atípicas escamosas de significado indeterminado, possivelmente não neoplásico, e as lesões intraepiteliais de baixo grau. Algumas variáveis apresentaram incompletude. Conclusão: a cobertura de exames Papanicolaou encontra-se baixa na região e a qualidade da informação insuficiente para monitorar a situação do câncer do colo do útero, pressupondo-se fragilidades na organização dos serviços.

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Section: Introductionunclassified

Rastreamento do câncer do colo do útero na região ampliada oeste de Minas Gerais

Rodrigues

Moreira

Alves

et al. 2016

R. Enferm. Cent. O. Min.

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“…No Brasil a prevalência varia de 1% a 11% (INCA 2008). Rosa (2009) em estudo realizado no Distrito Federal observou o HPV-56 com prevalência de 6,2% em mulheres HIV-1 soropositivas e, de acordo com os resultados obtidos, não há dados sobre a prevalência do HPV-56 em mulheres soronegativas.…”

Section: Resultsunclassified

Ocorrência de papilomavírus humano na cérvice uterina de mulheres da região ocidental da Amazônia Brasileira

et al. 2013

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A ocorrência do papiloma vírus humano (HPV) é um problema de saúde pública, pois tem sido associado ao câncer. O objetivo da pesquisa foi identificar a ocorrência de papilomavírus humano na cérvice uterina de mulheres da região ocidental da Amazônia Brasileira. O estudo foi realizado na capital de Rondônia, Porto Velho. Occurrence of human papillomavirus in uterine cervix of women in the western Brazilian Amazon ABSTRACTThe occurrence of human papillomavirus (HPV) is a public health problem, because it has been linked to cancer. The aim of this research was to identify the occurrence of human papillomavirus in uterine cervix of women in the western Brazilian Amazon. The study was conducted in the capital of Rondonia, Porto Velho. We identified the types of HPV, also we correlated molecular results with those of colpocytologic tests coming from 334 women who underwent preventive examinations at the Brazilian Unified Health System. From samples, we obtained genetic material of the human papillomavirus (HPV ADN) and amplified the 450-bp fragment from the conserved region of the L1 gene, which was submitted to restriction fragment length polymorphism (RFLP) analysis. Of the 334 samples analyzed, 31% were confirmed to have the presence of viral material (HPV ADN). We detected the existence of the following HPV types: 16, 18, 33, 53 and 58, which identifies the group of high oncogenic risk, with 72% (74/103) of occurrence. Also we found HPV types 11, 42 and 44, which belong to the group of low oncogenic risk, with 28% of occurrence. The recurrent profiles in the development of the analysis were HPV-16 and -18, with 17% and 16% respectively. We found that more than 80% of the samples that contained viral material did not show any abnormal cell in the cytology test. This finding reinforces the need to disseminate the use of molecular techniques in conventional diagnostics.

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“…It is estimated that more than 448 million new cases of curable sexually transmitted infections (syphilis, gonorrhea, chlamydia and trichomoniasis) occur annually throughout the world [2], and if viral infections (human papillomaviruses, herpes simplex virus and HIV) were considered, this estimate would be substantially higher [3]. It is a problem that concerns the international community due to its serious implications for individual and collective health [3,4]. …”

Section: Introductionmentioning

confidence: 99%

Sexually transmitted infections associated syndromes assisted in the primary health care in Northeast, Brazil

Cavalcante¹,

Araújo

Galvão

et al. 2012

BMC Public Health

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BackgroundThe lack of information on the care for sexually transmitted infections (STI) associated syndromes may contribute for its non-inclusion as prevention and control strategy for STI in Brazil. This study aims to analyze the cases of STI – Associated Syndromes assisted in primary health care center in a city in Northeast Brazil associating them with socio-demographic and behavioral variables.MethodsThis is a retrospective study that analyzed 5148 consultation forms and medical records of patients assisted in a primary health care center who presented at least one genital syndrome from 1999 to 2008. Was considered as dependent variables the genital syndromes and serologies for syphilis and HIV and as independent variables the socio-demographic and behavioral aspects. It was used Pearson’s chi-square test to analyze the differences between the categorical variables, with a significance level of 5%. It was performed a multivariate analysis through the multivariate logistic regression model with the variables with p <0.05. We used odds ratio with a confidence interval of 95%.ResultsThe most frequent syndromes were vaginal discharge and/or cervicitis (44%) and genital wart (42.2%). Most people were between 20 and 39 years old (70%) and women (74.2%). Genital ulcer was most prevalent among men (OR = 2.67; CI 95% 1.99-3.58) and people who studied more than eight years (OR = 1.33; CI 95% 1.00-1.75) and wart prevailed among men (OR = 3.92; IC 95% 3.36-4.57), people under 29 years old (OR = 1.81; CI 95% 1.59-2.07) and who studied more than eight years (OR = 1.75; CI 95% 1.54-1.99). The Venereal Disease Research Laboratory (VDRL) was positive in 7.3% of men and in 7.1% of women and the Anti-HIV in 3.1% of men and 0.7% of women.ConclusionVaginal discharge was the most frequent syndrome assisted in primary health care, followed by genital wart. The high prevalence of genital wart justifies the greater effort for the proper follow-up of these cases. Men presented more genital wart and ulcer and reported having more sexual partners, showing their need for a greater access and inclusion in health activities developed in primary health care in Brazil.

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Papilomavírus humano e neoplasia cervical

Cited by 45 publications

References 99 publications

Rastreamento do câncer do colo do útero na região ampliada oeste de Minas Gerais

Rastreamento do câncer do colo do útero na região ampliada oeste de Minas Gerais

Ocorrência de papilomavírus humano na cérvice uterina de mulheres da região ocidental da Amazônia Brasileira

Sexually transmitted infections associated syndromes assisted in the primary health care in Northeast, Brazil

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