Papular Eruptions in Adult Females

Noriega, Leandro Fonseca; Costa, Danielle Claudino de Oliveira; Pereira, Gilmayara Alves Abreu Maciel; Vieira, Marcelo Carvalho; Chiacchio, Nilton Di; Contin, Letícia Arsie

doi:10.1159/000445979

Cited by 3 publications

(1 citation statement)

References 12 publications

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“…The eruptive form of syringoma usually manifests itself with multiple 2-to-5 mm monomorphic papules that are shiny, firm, flat-topped and range in color between skin-colored, slightly yellowish or hyperpigmented [ 1 , 3 , 7 , 10 , 19 , 20 ]. The clinical presentation of our cases of eruptive syringomas is obviously divided into two types, first skin-colored to yellowish and second–discolored (erythematous, hyperpigmented).…”

Section: Discussionmentioning

confidence: 99%

Syringomatous dermatitis: a myth or an existing entity?

Hassab-El-Naby

Nouh

2023

Arch Dermatol Res

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Syringoma is rare disease that in classical variant occurs mainly on lower eyelids. In previously published researches, there is increasing evidence that eruptive syringomas must be discussed as an inflammatory dermal reaction pattern. And there was a proposal to change a name from eruptive syringoma to reactive syringomatous proliferation in appropriate cases. We conduct retrospective study on histopathological archived material to study the histopathological findings in cases of eruptive syringomas and correlate it with hypothesis that eruptive syringomas is not true adnexal neoplasms “de novo” but a hyperplastic response of the acrosyringium to an inflammatory process.According to obtained data and literature correlation, we can conclude that there is apparent diversity in eruptive syringomas. Part of cases can be calculated as neoplastic lesions arising “de novo,” and another part as reactive syringomatous proliferation due to preceding cutaneous inflammatory process. Thus, term “eruptive syringoma” may be changed in appropriate cases to a “reactive syringomatous proliferation.”Clinical variants of eruptive syringoma with evidence of underlying inflammatory process may be more responsive on types of treatments used for inflammatory disorders. Thus, more global clinicopathological correlative researches should be conducted and classification with terminology should be appropriately changed.

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Section: Discussionmentioning

confidence: 99%

Syringomatous dermatitis: a myth or an existing entity?

Hassab-El-Naby

Nouh

2023

Arch Dermatol Res

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Lo que esconde el «signo de Darier». Diagnóstico y comentario

Ramos¹,

Sánchez‐Martínez²,

Martínez

2021

Piel

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Late-Onset Eruptive Clear Cell Syringoma: A Case Report and Literature Review

Eittidachachote,

Triyangkulsri,

Rutnin

et al. 2024

CCID

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Eruptive syringoma, a rare subtype of syringoma, is a benign adnexal tumor arising from the eccrine sweat glands. It is characterized by multiple asymptomatic, flat-topped, brown-pigmented papules. The disease typically occurs during adolescence and young adulthood. The clear cell variant of syringoma, which histologically features ductal epithelial cells with clear cytoplasm, is relatively rare, while eruptive clear cell syringoma is even more infrequent. In this report, we present a case of a 64-year-old Thai woman who developed multiple erythematous to brownish papules on her right cheek, which eventually spread to the periorbital region, face, neck, and chest over five years. The diagnosis of late-onset eruptive clear cell syringoma was made based on the patient’s clinical manifestations and confirmed by histopathological examination. Notably, the patient was found to have impaired fasting plasma glucose upon screening, highlighting the potential association between clear cell syringoma and glucose metabolism abnormalities. This case report emphasizes the importance of considering this diagnosis in elderly patients presenting with eruptive papular dermatoses and underscores the need for metabolic screening in affected individuals.

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Papular Eruptions in Adult Females

Cited by 3 publications

References 12 publications

Syringomatous dermatitis: a myth or an existing entity?

Syringomatous dermatitis: a myth or an existing entity?

Lo que esconde el «signo de Darier». Diagnóstico y comentario

Late-Onset Eruptive Clear Cell Syringoma: A Case Report and Literature Review

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