Papular-purpuric gloves and socks syndrome

Estudio retrospectivo de 49 casos de infección aguda por parvovirus B19 en adultos

“…En 1990 se describió el «síndrome de lesiones purpúricas en guante y calcetín» 22 , y el parvovirus B19 está considerado como uno de los agentes etiológicos más importantes; de hecho se cree que es el responsable del cuadro en un 80% de los casos. Otros virus relacionados son el VEB, citomegalovirus, virus hepatitis B, virus varicelazoster, virus herpes 6 y 7, sarampión, rubéola y coxsackie 10 . Este síndrome se caracteriza por la aparición de eritema y edema pruriginoso, urente o doloroso en manos y pies, con una nítida delimitación al nivel de las muñecas y los tobillos.…”

Viral infections of the folds (intertriginous areas)

“…2,33 PVB19 infections are transmitted by air-carriage of respiratory droplets, and infectivity ceases after the eruption appears. 34 Infections caused by PVB19 can result in a wide spectrum of manifestations, which are usually influenced by the patient's immunologic status. While PVB19 infection is usually asymptomatic or can result in cutaneous disease in the immunocompetent host, it may lead to the development severe chronic anaemia or aplastic anemia in immunodeficient patients or…”

“…[34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50] Papular-purpuric gloves and socks syndrome is an acute self limiting pruritic dermatosis that affects the distal extremities in a gloves and socks pattern. PPGSS presents initially with erythema and popular oedema and may also be associated purpura and rarely petechiae.…”

“…The eruption may also involve the perioral and perianal skin or other sites of the skin in half of the patients. 3,34 PPGSS has mainly been described in young adults. 3,38,39 To date, more than 70 cases have been documented in the literature.…”

Petechial-Purpuric Rash, Leukopenia and Thrombocytopenia Associated Parvovirus B19

“…Parvovirus B19 infection can cause skin rashes such as erythema infectiosum (fifth disease), and petechial and/or purpuric lesions. Papular-purpuric gloves and socks syndrome (PPGSS) has more commonly been reported in adolescents and adults [2]. In addition some hematologic disorders may be seen as a complication.…”