Viral infections of the folds (intertriginous areas)

Moisture-Associated Skin Damage

“…1 The warm and humid local microclimate is also associated with changes in commensurate bacterial species found on the skin; coliform bacterial species, cyanobacteria, actinobacteria, and streptococcal infections found in moist skinfolds that may result in secondary cutaneous infections in skinfold as have various viral species, though the frequency and contribution of these potential pathogens to ITD are not well understood. 48,49 Multiple Candida species (C albicans, C glabrata, C tropicalis, C krusei, C parapsilosis, C dubliniensis, and C famata) are associated with ITD; in this case, treatment must incorporate both interventions to promote evaporation of the moisture created by perspiration with topical application of antifungal agents. 50 Yosipovitch and coworkers 51 measured cutaneous pH in a group of 50 participants with type 2 diabetes and a group of 40 controls and reported a significantly higher pH in diabetic individuals, suggesting diabetes mellitus may act as a risk factor for candidiasis in persons with ITD.…”

“…Friction is also postulated to play a significant role in the pathophysiology of ITD, particularly when moist skinfolds rub together 1. The warm and humid local microclimate is also associated with changes in commensurate bacterial species found on the skin; coliform bacterial species, cyanobacteria, actinobacteria, and streptococcal infections found in moist skinfolds that may result in secondary cutaneous infections in skinfold as have various viral species, though the frequency and contribution of these potential pathogens to ITD are not well understood 48,49. Multiple Candida species ( C albicans, C glabrata, C tropicalis, C krusei, C parapsilosis, C dubliniensis , and C famata ) are associated with ITD; in this case, treatment must incorporate both interventions to promote evaporation of the moisture created by perspiration with topical application of antifungal agents 50.…”

Caracterização das alterações cutâneas provocadas pelo novo Coronavírus SARS-CoV-2: uma revisão das novas evidências

“…A pele é considerada, pela comunidade médica, um órgão do corpo capaz de manifestar sinais de doenças internas, podendo indicar quando ocorrem disfunções metabólicas, neoplasias internas, doenças nutricionais, reações adversas a medicamentos ou doenças infecciosas sistêmicas, como as causadas pelos vírus da família Flaviviridae, Herpesviridae, Poxviridae, Papovaviridae, e Picornaviridae, entre outros causadores de doenças como, sarampo, escarlatina, doença de Chagas, tuberculose, sífilis, hanseníase, micoses profundas, leishmaniose e outras (ADIŞEN E. et al, 2015).…”