Paranasal Sinus Involvement in Metastatic Carcinoma

Abi-Fadel, Francois; Smith, Peter R.; Ayaz, Asim; Sundaram, Krishnamurthi

doi:10.1055/s-0032-1323157

Cited by 6 publications

(7 citation statements)

References 13 publications

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“…The rectal adenocarcinoma metastases to paranasal sinuses are exceedingly rare, notably in the frontal sinus [2 , 3] . The spread of tumor cells can be hematogenous or meningeal [5] . The rectal venous plexus communicates with the azygos system via the middle rectal vein, the common iliac vein and the ascending lumbar vein [4] .…”

Section: Discussionmentioning

confidence: 99%

“…Those veins are without valves, and an increase of abdominal pressure can drive tumor cells into the vertebral venous plexus [4] , which has been postulated as a possible route for the hematogenous spread of cancer cells to the head and neck [2] , since it communicates with the great venous plexus of the head and the plexus of the paranasal sinuses. The meningeal spread if it is reached is possible [5] .…”

Section: Discussionmentioning

confidence: 99%

“…MRI helps to evaluate the true extent of the lesion and can provide additional data, such as the presence or absence of skull base invasion and leptomeningeal involvement [3 , 5] .…”

Section: Discussionmentioning

confidence: 99%

“…Definitive diagnosis requires confirmation from biopsy [5] . Differential immunohistochemical staining patterns can be critical to the pathological distinction between these 2 entities in view of the resemblance of these lesions.…”

Section: Discussionmentioning

confidence: 99%

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Metastasis frontal sinus from rectal adenocarcinoma: A rare case

Lahfidi¹,

Imrani²,

Belkouchi³

et al. 2021

Radiology Case Reports

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Metastatic tumors of the nasal cavity and paranasal sinuses are much less common than primary cancer in this location. The clinical symptomatology is not specific. We report a case of frontal metastasis of a 49-year-old patient treated for a rectal adenocarcinoma without other secondary localizations. The treatment is based on radiotherapy or chemotherapy. Hence the value of recognizing sinus metastases and differentiating them from infection affection.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…MRI helps to evaluate the true extent of the lesion and can provide additional data, such as the presence or absence of skull base invasion and leptomeningeal involvement [3 , 5] .…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Metastasis frontal sinus from rectal adenocarcinoma: A rare case

Lahfidi¹,

Imrani²,

Belkouchi³

et al. 2021

Radiology Case Reports

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“…Other common metastases to the paranasal sinuses are breast, lung and prostate. 2 Only two cases have reported metastases from endometrial primaries to the paranasal sinuses. Scott et al 3 reported the first case of a stage 2A endometrioid-type endometrial adenocarcinoma spreading to the ethmoid sinus.…”

Section: Discussionmentioning

confidence: 99%

Metastatic endometrial cancer of the paranasal sinuses

Bashyam

Stewart

Potter

et al. 2018

annals

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Endometrial carcinoma is the fourth most common cancer affecting women in the UK. Its most frequent sites of spread are to the pelvic and para-aortic lymph nodes, vagina and peritoneum. We report a case of a 63-year-old woman with known endometrial cancer who presented with left facial swelling and eye displacement. Investigations revealed an expansile soft-tissue density mass arising within the bone, centred on the left zygoma, with exophytic extension into the left maxillary antrum, infratemporal fossa and inferiorly into the orbit. Endoscopic biopsies were taken and histology confirmed metastatic deposits of endometrial cancer. Clinicians should be aware that distant spread of endometrial cancer is linked with advanced disseminated disease and palliative treatments should be considered.

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Rare case of metastatic adenocarcinoma to the maxillary sinus

et al. 2021

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Colorectal carcinoma metastases to the head and neck are exceedingly rare. Patients may present with vague symptoms that may lead to a delay in diagnosis. We report the case of a 51-year-old man with a known history of stage IIIB colorectal adenocarcinoma who presented with right-sided molar tooth bleeding and right-sided palate swelling that led to difficulty speaking, eating and weight-loss of 15 pounds. Imaging studies revealed a 3.1×4.8×3 cm mass that was centred around the posterior aspect of the maxilla. Pathology revealed moderately differentiated intestinal type adenocarcinoma of colonic subtype, immune histochemistry was positive for CDX2, CK20 and MUC2, thus confirming metastatic disease to the maxilla. The patient is undergoing chemoradiation therapy for palliation of his symptoms. Clinicians should be aware of this potentional site of metastatic disease and suspect the diagnosis in a timely manner to avoid delays in making a diagnosis.

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Paranasal Sinus Involvement in Metastatic Carcinoma

Cited by 6 publications

References 13 publications

Metastasis frontal sinus from rectal adenocarcinoma: A rare case

Metastasis frontal sinus from rectal adenocarcinoma: A rare case

Metastatic endometrial cancer of the paranasal sinuses

Rare case of metastatic adenocarcinoma to the maxillary sinus

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