Parasitic Infection Surveillance in Mississippi Delta Children

Bradbury, Richard S.; Arguello, Irene; Lane, Meredith; Cooley, Gretchen; Handali, Sukwan; Dimitrova, Silvia D.; Nascimento, Fernanda S.; Jameson, Sam; Hellmann, Kathryn; Tharp, Michelle; Byers, Paul; Montgomery, Susan P.; Haynie, Lisa; Kirmse, Brian; Pilotte, Nils; Williams, Steven A.; Hobbs, Charlotte V.

doi:10.4269/ajtmh.20-0026

Cited by 11 publications

(9 citation statements)

References 16 publications

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“…We stored DNA extracts at −80°C and sent them to the CDC for real-time PCR analysis. At CDC, each sample was initially tested for inhibition and poor DNA extraction by a realtime PCR assay targeting the human cytochrome B gene (5). Samples positive by this inhibition and extraction control were then tested by multiparallel real-time PCR for STH (6).…”

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confidence: 99%

Parasitic Disease Surveillance, Mississippi, USA

Bradbury¹,

Lane²,

Arguello³

et al. 2021

Emerg. Infect. Dis.

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H uman populations in the state of Mississippi and the rest of the southeastern United States have historically been at risk for hookworm and other parasitic diseases (1,2). With improved sanitation and economic development, soil-transmitted helminths (STH), including the species Ascaris lumbricoides and Trichuris trichiura, were presumed to have been eliminated. However, a recent report of continued hookworm and strongyloidiasis transmission in a community without access to proper sanitation in Alabama, USA, has challenged this assumption (3).

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confidence: 99%

Parasitic Disease Surveillance, Mississippi, USA

Bradbury¹,

Lane²,

Arguello³

et al. 2021

Emerg. Infect. Dis.

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“…Within Native American communities, healthcare capacity is limited, with many required to travel hours to the nearest facility, and many communities do not have access to basic water or electricity (Brosemer et al., 2020; van Dorn, Conney, & Sabin, 2020). In the case of the Black Belt, unequal access to quality wastewater treatment has been connected to parasitic worm outbreaks in children—known as diseases of poverty (Bradbury et al., 2020; Meza, 2018). We found that hotspots have clearly emerged within this band and grown over time, especially across the Mississippi Delta (see Figure 7).…”

Section: Resultsmentioning

confidence: 99%

The US COVID Atlas: A dynamic cyberinfrastructure surveillance system for interactive exploration of the pandemic

Kolak

Lin

et al. 2021

Transactions in GIS

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Distributed spatial infrastructures leveraging cloud computing technologies can tackle issues of disparate data sources and address the need for data‐driven knowledge discovery and more sophisticated spatial analysis central to the COVID‐19 pandemic. We implement a new, open source spatial middleware component (libgeoda) and system design to scale development quickly to effectively meet the need for surveilling county‐level metrics in a rapidly changing pandemic landscape. We incorporate, wrangle, and analyze multiple data streams from volunteered and crowdsourced environments to leverage multiple data perspectives. We integrate explorative spatial data analysis (ESDA) and statistical hotspot standards to detect infectious disease clusters in real time, building on decades of research in GIScience and spatial statistics. We scale the computational infrastructure to provide equitable access to data and insights across the entire USA, demanding a basic but high‐quality standard of ESDA techniques. Finally, we engage a research coalition and incorporate principles of user‐centered design to ground the direction and design of Atlas application development.

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“…Globally, the seroprevalence of toxocariasis varies widely by climate and geographical region, being generally lower in industrialized temperate countries such as the USA (3.6%) ( Bradbury et al, 2020 ) and China (5.1%) ( Wang et al, 2020 ), and higher in lower-middle-income tropical countries such as Nigeria (92.4%) ( Ikotun et al, 2020 ), Honduras (88.6%) ( Hernández et al, 2020 ), Ghana (62.0%) ( Boyko et al, 2020 ), and Vietnam (59.0%) ( Van De et al, 2020 ). Our study reported a relatively low toxocariasis seroprevalence rate of 2.5% among allergic patients, 80% of whom were non-Kuwaiti residents originating from lower-middle-income South/Southeast Asian tropical countries (i.e., the Philippines, Sri Lanka and Bangladesh).…”

Section: Discussionmentioning

confidence: 99%