Parathyroid Autotransplantation During Thyroidectomy

Olson, John A.; DeBenedetti, Mary K.; Baumann, Dirk S.; Wells, Samuel A.

doi:10.1097/00000658-199605000-00003

Cited by 290 publications

(211 citation statements)

References 30 publications

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“…Although in most patients hypocalcemia recovers spontaneously, permanent hypocalcemia may be seen when the parathyroid glands are permanently damaged (8)(9)(10). In untreated patients with permanent hypoparathyroidism, serious complications such as cataracts, calcification of the basal ganglia and cerebellum, and papilla edema might develop (11-13).…”

Section: Discussionmentioning

confidence: 99%

Analysis of the factors that have an effect on hypocalcemia following thyroidectomy

Kalyoncu¹,

Gönüllü²,

Gedik³

et al. 2014

UCD

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Objective: The incidence of and risk factors for hypocalcemia following thyroidectomy were evaluated in this study. Material and Methods:One hundred and ninety thyroidectomy patients were evaluated retrospectively for factors that might contribute to postoperative hypocalcemia; age, hyperthyroidism, malignancy, the extent of surgery (total/near total/subtotal thyroidectomy), cervical lymph node dissection, and incidental parathyroidectomy. Results:The rate of transient hypocalcemia/hypoparathyroidism was 19.47%, with a permanent hypoparathyroidism rate of 4.74%. Factors affecting the development of transient hypocalcemia were found as being operated for hyperthyroidism, and use of total thyroidectomy as the surgical method. Total thyroidectomy increased the risk of postoperative hypocalcemia by 3.16 fold. Patients undergoing operations for hyperthyroidism had a 2.3 fold increase, and those undergoing total thyroidectomy had a 3.16 fold risk of postoperative hypocalcemia. Conclusion:Hyperthyroidism surgery and total thyroidectomy lead to a higher risk of developing early postoperative or transient hypocalcemia. According to our results, no significant relationship could be established between any of the study parameters and persistent hypocalcemia.

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Section: Discussionmentioning

confidence: 99%

Analysis of the factors that have an effect on hypocalcemia following thyroidectomy

Kalyoncu¹,

Gönüllü²,

Gedik³

et al. 2014

UCD

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“…Bilateral central (compartment VI) node dissection may improve survival (compared to historic controls) and reduce the risk for nodal recurrence (76,103). This central compartment dissection can be achieved with low morbidity in experienced hands (104)(105)(106)(107).…”

Section: What Is the Appropriate Operation For Differentiated Thyroidmentioning

confidence: 99%

Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Taskforce

Cooper

Doherty

Haugen

et al. 2006

Thyroid

1,923

938

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“…It has been generally accepted that half of one normal parathyroid gland can produce sufficient parathyroid hormone (PTH)2, 3. To avoid postoperative hypocalcaemia, parathyroid autotransplantation can be performed, although the results have been controversial4, 5.…”

Section: Introductionmentioning

confidence: 99%

Parathyroid gland angiography with indocyanine green fluorescence to predict parathyroid function after thyroid surgery

Fortuny

Belfontali

Sadowski

et al. 2016

British Journal of Surgery

151

130

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BackgroundPostoperative hypoparathyroidism remains the most common complication following thyroidectomy. The aim of this pilot study was to evaluate the use of intraoperative parathyroid gland angiography in predicting normal parathyroid gland function after thyroid surgery.MethodsAngiography with the fluorescent dye indocyanine green (ICG) was performed in patients undergoing total thyroidectomy, to visualize vascularization of identified parathyroid glands.ResultsSome 36 patients underwent ICG angiography during thyroidectomy. All patients received standard calcium and vitamin D supplementation. At least one well vascularized parathyroid gland was demonstrated by ICG angiography in 30 patients. All 30 patients had parathyroid hormone (PTH) levels in the normal range on postoperative day (POD) 1 and 10, and only one patient exhibited asymptomatic hypocalcaemia on POD 1. Mean(s.d.) PTH and calcium levels in these patients were 3·3(1·4) pmol/l and 2·27(0·10) mmol/l respectively on POD 1, and 4·0(1.6) pmol/l and 2·32(0·08) mmol/l on POD 10. Two of the six patients in whom no well vascularized parathyroid gland could be demonstrated developed transient hypoparathyroidism. None of the 36 patients presented symptomatic hypocalcaemia, and none received treatment for hypoparathyroidism.Conclusion PTH levels on POD 1 were normal in all patients who had at least one well vascularized parathyroid gland demonstrated during surgery by ICG angiography, and none required treatment for hypoparathyroidism.

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Parathyroid Autotransplantation During Thyroidectomy

Cited by 290 publications

References 30 publications

Analysis of the factors that have an effect on hypocalcemia following thyroidectomy

Analysis of the factors that have an effect on hypocalcemia following thyroidectomy

Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Taskforce

Parathyroid gland angiography with indocyanine green fluorescence to predict parathyroid function after thyroid surgery

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