Parental report of sleep problems in Down syndrome

Breslin, Jennifer H.; Edgin, Jamie O.; Bootzin, Richard R.; Goodwin, James L.; Nadel, Lynn

doi:10.1111/j.1365-2788.2011.01435.x

Cited by 72 publications

(97 citation statements)

References 23 publications

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“…6,21,22 The CSHQ yields both a total score and eight subscale scores, reflecting key sleep domains in school-aged children. Here we report parent ratings of sleep-disordered breathing and daytime sleepiness subscales, with higher scores reflecting poorer sleep behaviors.…”

Section: Parent-reported Sleepmentioning

confidence: 99%

Obstructive sleep apnea syndrome and cognition in Down syndrome

Breslin

Spanò

Bootzin

et al. 2014

Develop Med Child Neuro

180

174

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ACTBArizona Cognitive Test Battery AHI Apnea-hypopnea index IED Intra-extra dimensional set shift OSAS Obstructive sleep apnea syndrome PSG PolysomnographyAIM Good-quality sleep is essential for normal learning and memory. Sleep fragmentation and disrupted sleep architecture are commonly observed throughout the lifespan of individuals with Down syndrome, a condition marked by cognitive deficits emerging within the first few months of life. While obstructive sleep apnea syndrome (OSAS) is known to contribute to the loss of sleep quality in Down syndrome, its relation to cognitive and behavioral impairment remains poorly understood.METHOD Using ambulatory polysomnography, we measured sleep in an unreferred community-based sample of 38 individuals with Down syndrome (15 males, 23 females; mean age 9y 7mo (SD 1y 9mo), range 7-12y). Cognitive outcomes were assessed with the Arizona Cognitive Test Battery, a set of psychometric measures designed and validated for this population.RESULTS Among children with Down syndrome, mean Verbal IQ score (p=0.006) was 9 points lower in those with comorbid OSAS (apnea-hypopnea index >1.5) than in those without OSAS, and performance on measures of cognitive flexibility was poorer (p=0.03). In addition, those with OSAS showed increased light-stage sleep (p=0.009) at the expense of slow-wave sleep (p=0.04).INTERPRETATION These findings demonstrate a relation between OSAS and cognitive outcomes in Down syndrome. More work is required to fully understand the mechanisms underlying the links between poor sleep and impaired cognitive function. Overall, these findings highlight the importance of adequate sleep in typically and atypically developing populations.Down syndrome (trisomy 21) is the most common genetically defined cause of intellectual disability, with over 300 000 affected individuals residing in the United States alone. 1 The condition is characterized by decline of IQ during the infant and toddler years, well-documented deficits in the assimilation and expressive use of language, and impairments in cognitive flexibility and memory.2 As a result of alterations in craniofacial and oral musculature development and low muscle tone, individuals with Down syndrome are exceptionally vulnerable to obstructive sleep apnea syndrome (OSAS) from infancy, with estimates of the prevalence of the condition ranging from 30% to as high as 80%. [3][4][5] Ashworth et al. 6 have recently described the extent of sleep disruption in individuals with Down syndrome, noting that such individuals displayed more fragmented sleep than those with Williams syndrome, another intellectual disability. Because of the extent of their sleep disruption, individuals with Down syndrome could potentially suffer ill effects during critical periods of cognitive development.OSAS occurs when the upper airway becomes intermittently obstructed during sleep, resulting in incomplete ventilation, blood gas irregularities, and sleep fragmentation. It is best diagnosed with polysomnography (PSG), the criterion standard for sle...

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Section: Parent-reported Sleepmentioning

confidence: 99%

Obstructive sleep apnea syndrome and cognition in Down syndrome

Breslin

Spanò

Bootzin

et al. 2014

Develop Med Child Neuro

180

174

View full text Add to dashboard Cite

show abstract

“…Esta pesquisa foi a primeira a investigar os aspectos do sono e de atenção em escolares com SD e SW e salientou a necessidade de se investir em estudos futuros para melhor contribuições da atenção, do sono e sua influência nesses dois grupos (ASHWORTH et al, 2014). No entanto, observou-se que há caracterísicas comuns aos dois grupos com se sem deficiência, tais como ronco, agitação noturna, irritação, respiração ruidosa, pausas respiratórias, déficit de atenção, instabilidade de humor e dificuldade de socialização, cooperação (MARTINEZ, 1999;GOTTLIEB;CHASE;VEZIN, 2004;VALERA;DEMARCO;ANSELMO-LIMA, 2004;BRESLIN et al, 2011;ASHWORTH, et al, 2013;BUCKHALT, 2013). Observou-se que o exame indicado para avaliar os DRS é a polissonografia (MACEDO; COLOMBINI; PINTO, 2010).…”

Section: Desta Forma O Estudo Que Bonuck Et Al (2011) Realizaram Nunclassified

“…Porém, devido aos elevados custos do exame, muitas pesquisas têm avaliado a qualidade do sono por meio de questionários padronizados do sono. Tal situação tem sido recorrente no diagnóstico dos escolares com e sem deficiência (MAAS et al, 2009;BRESLIN, 2011). Outro instrumento que os pesquisadores dos distúrbios do sono têm utilizado para avaliação das crianças e adolescentes com deficiência é a actigrafia.…”

Section: Desta Forma O Estudo Que Bonuck Et Al (2011) Realizaram Nunclassified

Implicações Dos Distúrbios Respiratórios Do Sono Em Alunos Com Deficiência Intelectual: Revisão Sistemática

Godoy

Almeida

2017

Periferia

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ResumoNos últimos anos, as pesquisas sobre os distúrbios respiratórios do sono em crianças e adolescentes com desenvolvimento típico têm ampliado. As pesquisas constataram que o sono de má qualidade interfere nas competências físicas e intelectivas do ser humano. Como seria a influência desse distúrbio em educandos com deficiência intelectual? O estudo teve por objetivo verificar e analisar nas publicações científicas a influência dos distúrbios respiratórios do sono em escolares com deficiência intelectual. Trata-se um delineamento sistemático de cunho qualitativo. O levantamento foi realizado no período que compreende os anos de 2000 a 2016. Os artigos estavam indexados bases de dados EBSCOhost, DOAJ, ERIC e SciELO Brasil. Os descritores utilizados foram i) distúrbios respiratórios do sono e dificuldade de aprendizagem; ii) distúrbios respiratórios do sono e deficiência intelectual; iii) distúrbios respiratórios do sono e etiologia da deficiência intelectual; iv) distúrbios respiratórios do sono e déficit intelectual. A busca também foi realizada em língua inglesa, a saber: i) sleep-disordered breathing and learning disability; ii) sleep-disordered breathing and Intellectual disability; iii) sleepdisordered breathing and Etiology intellectual disability; iv) sleep-disordered breathing and Intellectual deficit. Com base nesses descritores, foram encontradas 43 pesquisas. Entretanto, considerando-se os requisitos elegidos para este estudo, apenas sete artigos compuseram o corpus final de análise. Desses, quatro eram estudos experimentais, dois de revisões de literatura e um do tipo longitudinal. As pesquisas revelaram que a influência dos distúrbios do sono junto às crianças e aos adolescentes com deficiência intelectual é recente e limitada, porém, tais distúrbios respiratórios do sono interferem significativamente na qualidade de vida, bem como nos aspectos de desenvolvimento e aprendizagem dos alunos com deficiência intelectual. Esse levantamento ressaltou a necessidade de pesquisas brasileiras, sobretudo em Educação Especial, de se preocuparem em inserir os distúrbios respiratórios do sono nos estudos junto a essa população escolar.Palavras-chave: educação especial; deficiência intelectual; distúrbios respiratórios do sono; revisão sistemática

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“…Bedtime resistance, sleep anxiety, night waking, parasomnias and daytime sleepiness have all been reported commonly in children with DS [11,[13][14][15]24]. Carter et al [11] used the Child Sleep Habits Questionnaire (CSHQ) and found that parents universally reported sleep problems in school-aged children with DS that persisted into teenage years.…”

Section: Prevalence Of Sleep Disorders In Children With Down Syndromementioning

confidence: 99%

“…Large inter-individual differences are seen within the DS population and numerous factors including genetics, epigenetics, early neural development and the environment are thought to have a role in how the DS phenotype expresses itself in each individual [7]. Variation in sleep patterns and sleep disruption, has been highlighted as another potential factor that could contribute to the wide phenotypic differences in DS; individuals with DS often have sleep fragmentation due to common co-existing sleep disorders [8][9][10][11][12][13][14][15]. The degree of sleep difficulties in an individual with DS may be important in determining their predisposition to cognitive decline, by contributing to pathological ageing [16].…”

Section: Introductionmentioning

confidence: 99%

Sleep in Down Syndrome

Chawla¹,

Heussler²

2018

Advances in Research on Down Syndrome

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Sleep disorders are common, often overlooked problem in Down syndrome, particularly during childhood. Comorbidities such as congenital heart disease often present early and management of these needs to take priority. However, this can result in the lack of early development of good sleep habits and may also lead to the perception that sleep issues are an expected problem in children with Down syndrome, which do not require intervention. Studies have shown that sleep problems continue to be under-reported by parents of children with Down syndrome, even though conditions such as obstructive sleep apnoea are up to six times more common in this population. Therefore an understanding of the nature of sleep problems in Down syndrome is important for anyone working with this group. In this chapter we provide an overview of this topic, highlighting the key sleep issues encountered by children with Down syndrome, as well as providing a general approach to evaluation and management.

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Parental report of sleep problems in Down syndrome

Abstract: Children with DS are at risk for developing symptoms of sleep disordered breathing, and may have additional sleep problems that are unrelated to sleep disordered breathing.

Cited by 72 publications

References 23 publications

Obstructive sleep apnea syndrome and cognition in Down syndrome

Obstructive sleep apnea syndrome and cognition in Down syndrome

Implicações Dos Distúrbios Respiratórios Do Sono Em Alunos Com Deficiência Intelectual: Revisão Sistemática

Sleep in Down Syndrome

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