Parkinson's disease, cognition and aging Clinical, neuropsychological, electrophysiological and cranial computerized tomographic assessment

A dopamine agonist, pramipexole, and cognitive functions in Parkinson's disease

“…Diminished 9 performance in this test may be due to difficulty to name the objects or to impaired visual organization. Verbal disturbances, primarily associated with word finding, are common in PD patients (21).…”

Event-related potentials and cognition in Parkinson’s disease: An integrative review

“…The degree of global cognitive impairment has been linked to P3b latency by studies showing correlations between P3b latency and neuropsychological measures of general intelligence (Bodis-Wollner et al, 1995;Hansch et al, 1982;Katsarou et al, 2004), processing speed (O'Donnell et al, 1987), and, most frequently, the global score on the MMSE (Lukhanina et al, 2009;Maeshima et al, 2002;Matsui et al, 2007;Sartucci et al, 1990;Stamenović et al, 2005;Tachibana et al, 1997; but see Elwan et al, 1996;Lukhanina et al, 2008).…”

“…Specifically, P3b latency appears to be related to prototypical executive functions such as set-shifting (Iijima et al, 2000;Katsarou et al, 2004;Stamenović et al, 2005; but see Stanzione et al, 1998), trail-making (Matsui et al, 2007;Stamenović et al, 2005; but see Elwan et al, 1996), verbal fluency (BodisWollner et al, 1995;Chen et al, 2006), working memory (O'Donnell et al, 1987), and planning (Kim et al, 1995), even in non-demented patients. However, to date it is not clear whether the association between P3b latency and executive functioning in PD is actually specific, because previous studies did not control for the variance shared with measures of global cognitive ability.…”

Dopaminergic medication alters auditory distractor processing in Parkinson's disease

“…Some of these studies (Elwan et al, 1996;Graham, Yiannikas, Gordon, Coyle, & Morris, 1990;Green et al, 1996;Karayanidis, Andrews, Ward, & Michie, 1995) found no differences between PD patients and healthy controls, whereas others reported reduced P3b amplitude (Koberskaia, Zenkov, and Iakhno (2003)), or prolonged P3b latency (Stanzione et al (1998)) in PD patients compared to healthy controls. Additionally, Bodis-Wollner et al (1995) have found that the P3b latencies in both auditory and visual oddball tasks significantly but differentially correlate with scores on cognitive tests.…”