Parkinson’s Disease Related Depression and Anxiety: A 22-Year Bibliometric Analysis (2000-2022)

Zhang, Tong; Rui, Yang; Pan, Juhua; Huang, Shijing

doi:10.2147/ndt.s403002

Cited by 14 publications

(10 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While the primary clinical manifestation of PD is motor symptoms, non-motor symptoms like anxiety and depression are also the most common and significant psychiatric features of PD ( Landau et al, 2016 ). Moreover, these two symptoms often accompany PD patients and may persist throughout the disease course ( Zhang et al, 2023 ). In addition, cognitive deficits related to learning and memory abilities have been observed in more than 15% of PD patients ( Svenningsson et al, 2012 ).…”

Section: Research On Non-depressive Conditionsmentioning

confidence: 99%

Exploring the multifaceted potential of (R)-ketamine beyond antidepressant applications

Zhang,

Pu,

Liu

et al. 2024

Front. Pharmacol.

View full text Add to dashboard Cite

(R, S)- and (S)-ketamine have made significant progress in the treatment of treatment-resistant depression (TRD) and have become a research focus in recent years. However, they both have risks of psychomimetic effects, dissociative effects, and abuse liability, which limit their clinical use. Recent preclinical and clinical studies have shown that (R)-ketamine has a more efficient and lasting antidepressant effect with fewer side effects compared to (R, S)- and (S)-ketamine. However, a recent small-sample randomized controlled trial found that although (R)-ketamine has a lower incidence of adverse reactions in adult TRD treatment, its antidepressant efficacy is not superior to the placebo group, indicating its antidepressant advantage still needs further verification and clarification. Moreover, an increasing body of research suggests that (R)-ketamine might also have significant applications in the prevention and treatment of medical fields or diseases such as cognitive disorders, perioperative anesthesia, ischemic stroke, Parkinson’s disease, multiple sclerosis, osteoporosis, substance use disorders, inflammatory diseases, COVID-19, and organophosphate poisoning. This article briefly reviews the mechanism of action and research on antidepressants related to (R)-ketamine, fully revealing its application potential and development prospects, and providing some references and assistance for subsequent expanded research.

show abstract

Section: Research On Non-depressive Conditionsmentioning

confidence: 99%

Exploring the multifaceted potential of (R)-ketamine beyond antidepressant applications

Zhang,

Pu,

Liu

et al. 2024

Front. Pharmacol.

View full text Add to dashboard Cite

show abstract

“…The HAMD 35 is a scale for the diagnosis of depression. Given the prevalence of co-occurring anxiety and depression among patients with PD, 36 it is indeed valuable to incorporate HAMD to gauge the severity of depression. This approach allows you to explore potential correlations between anxiety, depression and the effectiveness of acupuncture.…”

Section: Outcome Measurementioning

confidence: 99%

Efficacy of acupuncture (Jin’s three-needle) on motor symptoms and anxiety in patients with Parkinson’s disease: protocol for a multicentre, randomised, assessor-blinded clinical trial

Liu,

Fan,

Leong

et al. 2024

BMJ Open

View full text Add to dashboard Cite

IntroductionParkinson’s disease (PD) has a significant impact on a substantial number of individuals in China. Notably, 31% of patients with PD also grapple with the additional burden of anxiety. This dual challenge of managing both PD and anxiety underscores the complexity of the condition and the diverse range of symptoms patients may experience. Considering the circumstances, the cost and potential drawbacks associated with traditional antiparkinsonian drugs become increasingly relevant. Acupuncture emerges as a significant non-pharmacological adjunct therapy. Offering a potentially safer and more cost-effective option, acupuncture addresses the pressing need for holistic and complementary treatments that may alleviate both the motor symptoms of PD and the accompanying anxiety.Methods and analysisThis is a multicentre, randomised controlled and assessor-blind trial. A total of 210 eligible patients with PD will be randomly assigned (1:1) to Jin’s three-needle (JTN) acupuncture group or waitlist (WL) group. Patients in the JTN group will receive acupuncture therapy three times per week for 4 weeks. Patients in the WL group will maintain their original dosage of antiparkinsonian drugs and receive acupuncture therapy after the observation period. The primary outcome measure will be the Unified Parkinson’s Disease Rating Scale score. The secondary outcome measures will be the scores of the Hoehn-Yahr Rating Scale, Unified Dyskinesia Rating Scale, Non-Motor Symptoms Scale, 39-item Parkinson’s Disease Questionnaire, Parkinson Anxiety Scale, Hamilton Anxiety Scale, Hamilton Depression Scale, Zarit burden interview and the level of cortisol and adrenocorticotropic hormone. The evaluation will be executed at baseline, the end of the treatment and a follow-up period.Ethics and disseminationThe study was approved by the Ethics Committee of the First Affiliated Hospital of Guangzhou University of Chinese Medicine (K[2023]014). All patients have to provide written, informed consent. The study will be disseminated through presentations in peer-reviewed international journals and at national and international conferences.Trial registration numberChinese Clinical Trial Registry; ChiCTR2300074675.

show abstract

“…It also leads to impairment of cognition and mood. [42] One study showed significant improvements in proprioception, motion range, and quality of life for Parkinson's patients through rebound therapy compared to treadmill running. [43] However, evidence supporting its effectiveness is limited, and further trials, such as the Lisbon Intensive Falls Trampoline Training study, are required.…”

Section: Balancementioning

confidence: 99%

Springing to Life: Unveiling the Transformative Effects of Trampoline Bouncing on Human Health

Bereza,

Sokołowska,

Kulak

et al. 2024

J Educ Health Sport

View full text Add to dashboard Cite

Introduction and Objective: In the modern era, where non-communicable diseases account for 74% of deaths, physical activity plays a crucial role in reducing mortality rates, particularly from cardiovascular causes. This article aims to assess the benefits and risks of trampoline bouncing as an exercise modality. State of Knowledge: Scientific evidence predominantly focuses on rebounding-related injuries, overshadowing the relatively underexplored benefits of trampolining. Cardiovascular advantages, including increased VO2max, are notable, with mini-trampoline exercise proving more effective than traditional running. Trampolining exhibits the potential to reduce BMI and weight, impacting cardiovascular risk factors while contributing to bone strength and mental well-being. Positive outcomes are suggested for specific groups, such as Parkinson's patients and children with disabilities. Summary: Trampoline rebounding, particularly with mini-trampolines, presents an enjoyable exercise form with significant health benefits, encompassing enhanced cardiovascular endurance, improved balance, and positive effects on bone structure and mental well-being. Despite prevalent injuries associated with trampoline use, the article highlights effective preventive measures. In conclusion, trampoline bouncing holds promise as a valuable component of a healthy lifestyle, provided adequate precautions are taken to mitigate associated risks.

show abstract

Parkinson’s Disease Related Depression and Anxiety: A 22-Year Bibliometric Analysis (2000-2022)

Cited by 14 publications

References 63 publications

Exploring the multifaceted potential of (R)-ketamine beyond antidepressant applications

Exploring the multifaceted potential of (R)-ketamine beyond antidepressant applications

Efficacy of acupuncture (Jin’s three-needle) on motor symptoms and anxiety in patients with Parkinson’s disease: protocol for a multicentre, randomised, assessor-blinded clinical trial

Springing to Life: Unveiling the Transformative Effects of Trampoline Bouncing on Human Health

Contact Info

Product

Resources

About