2014
DOI: 10.1186/1471-2474-15-265
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Parsonage-Turner syndrome following post-exposure prophylaxis

Abstract: BackgroundThe ‘Parsonage-Turner syndrome’ (PTS) is a rare but distinct disorder with an abrupt onset of shoulder pain, followed by weakness and atrophy of the upper extremity musculature, and a slow recovery requiring months to years. To our best knowledge, this is the first case describing symptoms and signs of PTS following the administration of a post-exposure prophylaxis (PEP) regimen against possible human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infection.Case presentationA 25-year-old Ca… Show more

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Cited by 23 publications
(31 citation statements)
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“…The diagnosis of PTS is primarily made through clinical history/ symptoms and physical exam findings. Additional diagnostic work-up, including imaging and electromyography may support the diagnosis of PTS often by excluding other etiologies [5]. The differential diagnosis for PTS includes primary glenohumeral joint pathology, however PTS can be distinguished from primary joint pathology through appropriate clinical history, physical exam, and imaging findings.…”
Section: Introductionmentioning
confidence: 99%
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“…The diagnosis of PTS is primarily made through clinical history/ symptoms and physical exam findings. Additional diagnostic work-up, including imaging and electromyography may support the diagnosis of PTS often by excluding other etiologies [5]. The differential diagnosis for PTS includes primary glenohumeral joint pathology, however PTS can be distinguished from primary joint pathology through appropriate clinical history, physical exam, and imaging findings.…”
Section: Introductionmentioning
confidence: 99%
“…Treatment of PTS predominantly focuses on pain management with opiates, NSAIDs, and neuroleptics [1]. Additionally, there is some evidence to suggest that the use of early oral corticosteroid therapy may be beneficial [5].…”
Section: Introductionmentioning
confidence: 99%
“…Indeed, BT has immunogenic properties, and the main concern in this regard has been the development of neutralizing antibodies by the patient . It is thus conceivable that a similar mechanism, akin to BN occurring after vaccinations, may occur here. So far, there is no evidence to conclusively link BT injections to BN, and to substantiate a pathophysiological link.…”
Section: Discussionmentioning
confidence: 99%
“…The aetiology of most cases of BN remains unclear, but there is evidence suggesting an autoimmune process with various triggers, including vaccinations or immunomodulation (IL2‐ and interferon therapy) …”
Section: Introductionmentioning
confidence: 99%
“…When considering the differential diagnosis, musculoskeletal disorders of shoulder, CR, poliomyelitis, amyotrophic lateral sclerosis, herpes zoster, tumors of spinal cord or brachial plexus, posterior interosseous nerve palsy, traumatic or compressive nerve injuries should be considered (12,13).…”
Section: Discussionmentioning
confidence: 99%