Part XXIII. Synthesis and characterization of platinum(IV) complexes with O,O′-dialkyl esters of (S,S)-ethylenediamine-N,N′-di-2-(3-methyl)butanoic acid and bromido ligands. Antimicrobial, antibiofilm and antioxidant screening

Jević, Verica V.; Stefanović, Olgica D.; Radojević, Ivana D.; Vasić, Sava M.; Čomić, Ljiljana R.; Đinović, Vesna M.; Trifunović, Srećko R.

doi:10.1016/j.ica.2015.12.001

Cited by 5 publications

(2 citation statements)

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“…15,16 Titanium, tin, gallium and molybdenum have also all been shown to have antimicrobial potential in various forms. [17][18][19] Vanadium-based compounds have previously displayed antimicrobial properties in vanadium peroxidase reactions against Streptococcus mutans planktonic and biolm morphologies.…”

Section: -9mentioning

confidence: 99%

“… 14 Palladium, platinum and rhodium are all platinum group metals which share similar physical and chemical properties resulting in similar antimicrobial potentials. 15,16 Titanium, tin, gallium and molybdenum have also all been shown to have antimicrobial potential in various forms. 17–19 Vanadium-based compounds have previously displayed antimicrobial properties in vanadium peroxidase reactions against Streptococcus mutans planktonic and biofilm morphologies.…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial synergy of cationic grafted poly(para-phenylene ethynylene) and poly(para-phenylene vinylene) compounds with UV or metal ions against Enterococcus faecium

et al. 2018

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The rise in multidrug resistant bacteria is an area of growing concern and it is essential to identify new biocidal agents. Cationic grafted compounds were investigated for their antimicrobial properties using minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) tests. Synergy testing was carried out using the compounds in the presence of ultraviolet (UV). Fractional inhibitory concentration (FIC) and fractional bactericidal concentration (FBC) tests were carried out using the cationic molecules in conjunction with metal ion solutions of gold, silver, palladium, platinum, rhodium, titanium, tin, vanadium and molybdenum. Individually, the cationic compounds containing quaternary amines, polyphenylene vinylene (PPV) with long polyacrylate grafts (PPV-g-PMETAC (HMw)), polyphenylene ethylene (PPE) with long polyacrylate grafts (PPE-g-PMETAC (HMw)), polyphenylene vinylene (PPV) with short polyacrylate grafts (PPV-g-PMETAC (LMw)) and polyphenylene ethylene (PPE) with short polyacrylate grafts (PPE-g-PMETAC (LMw)) were effective against Enterococcus faecium. The most successful compound under UV was PPV-g-PMETAC (HMw). Following the FICs, palladium and rhodium ion solutions caused a synergistic reaction with all four tested compounds. The presence of conjugated bonds in the cationic molecules increased its antimicrobial activity. These results suggest that the chemical backbone of the compounds, alongside the chain lengths and chain attachment affect the antimicrobial efficacy of a compound. These factors should be taken into consideration when formulating new biocidal combinations.

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