2006
DOI: 10.1271/bbb.70.1218
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Partial Characterization and Immunostimulatory Effect of a Novel Polysaccharide–Protein Complex Extracted fromPhellinus linteus

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Cited by 81 publications
(51 citation statements)
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“…Kim et al [16] demonstrated that a novel polysaccharide-protein complex extracted from PL markedly increased B-cell proliferation, production of cytokines and nitric oxide from macrophages, and NK cell-mediated killing of YAC-1 lymphoma cells in vitro. These results suggest that PL is a biological response modifier.…”
Section: Immunomodulationmentioning
confidence: 99%
“…Kim et al [16] demonstrated that a novel polysaccharide-protein complex extracted from PL markedly increased B-cell proliferation, production of cytokines and nitric oxide from macrophages, and NK cell-mediated killing of YAC-1 lymphoma cells in vitro. These results suggest that PL is a biological response modifier.…”
Section: Immunomodulationmentioning
confidence: 99%
“…the polysaccharide-protein complex (ppc) extracted from P. linteus demonstrated immunomodulatory effects through the stimulation of the proliferation of B-cells in murine splenocytes and the induction of production of interleukin (il)-1β, il-6 and tumor necrosis factor-α (tnF-α) in peritoneal macrophages (26). moreover, ppc up-regulated the macrophage-mediated tumoricidal activity by the secretion of nO and enhanced the natural killer (nK) cell cytotoxicity (26). On the other hand, protein-bound polysaccharide (pBp) isolated from P. linteus demonstrated a direct effect on cancer cells (27).…”
Section: The Anticancer Activity Of Isolated Compoundsmentioning
confidence: 99%
“…These natural components include Punica granatum L. Semen (7), Meconopsis horridula (8), Gentianae Macrophyllae Radix Flos (9), Tinospora sinensis (10), Caryophylli Flos (11), Amomi Fructus Rotundus and Cassiae Semenv (12) that are known to be potent in promoting blood circulation to remove blood stasis and preventing osteoarthritis. In addition, Cinnamomi Cortex (13), Zingiberis Rhizoma, Carthami Flos (14) and Polygonati Rhizoma (15) are components of jiangu with anti-inflammatory and analgesic effects. The jiangu capsule acts to promote blood circulation, eliminate cold and dampness from the body and reduce inflammation.…”
Section: Introductionmentioning
confidence: 99%