The present chapter contains the material taught within the module P2 of FAP 2004. The purpose of this intensive course is first to provide an introduction to "algebraic analysis". This fashionable though quite difficult domain of pure mathematics today has been pioneered by V.P. Palamodov, M. Kashiwara and B. Malgrange around 1970, after the work of D.C. Spencer on the formal theory of systems of partial differential equations. We shall then focus on its application to control theory in order to study linear control systems defined by partial differential equations with constant or variable coefficients, also called multidimensional control systems, by means of new methods from module theory and homological algebra. We shall revisit a few basic concepts and prove, in particular, that controllability, contrary to a well established engineering tradition or intuition, is an intrinsic structural property of a control system, not depending on the choice of inputs and outputs among the control variables or even on the presentation of the control system. Our exposition will be rather elementary as we shall insist on the main ideas and methods while illustrating them through explicit examples. Meanwhile, we want to stress out the fact that these new techniques bring striking results even on classical control systems of Kalman type !.