Partial priapism secondary to tamsulosin: a case report and review of the literature

Kılınç, Mehmet; Piskin, Mesut; Güven, Selçuk; Gürbüz, Recai; Ödev, Kemal; Kaynar, Mehmet

doi:10.1111/j.1439-0272.2008.00908.x

Cited by 28 publications

(29 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the remaining 10 cases the issue was not addressed and the images of the condition were unclear with regard to a septum [1][2][3][11][12][13]21,22].…”

Section: Literature Reviewmentioning

confidence: 99%

“…In addition to a painful mass in the perineum, which was how the condition presented in all cases, some of the patients experienced erectile dysfunction, and a few complained about dysuria or a decrease in the calibre of the urinary stream. IPT has been associated with haematological diseases such as homocysteinaemia [1], sickle cell disease [2] and congenital spherocytosis [3], cocaine [4] and marijuana abuse [2], a prior history of priapism [2,5], (vigorous or prolonged) sexual activity [2,[4][5][6][7][8][9][10], tamsulosin [11], bicycle riding [12][13][14][15] and aeroplane flight [12]. IPT is always located in the proximal part of the CC while the distal CC remains flaccid.…”

Section: Literature Reviewmentioning

confidence: 99%

See 1 more Smart Citation

Idiopathic partial thrombosis of the corpus cavernosum: Aetiology, diagnosis and treatment

Hulth¹,

Albersen

Fode³

et al. 2012

Scandinavian Journal of Urology

View full text Add to dashboard Cite

Idiopathic partial thrombosis of the corpus cavernosum (IPT) is a rare cause of perineal pain involving thrombosis within the proximal corpora cavernosa. This article clarifies the aetiology and makes recommendations on diagnosis and treatment. Three cases are described and a systematic review of the literature is presented. Magnetic resonance imaging (MRI) scans of the penis conducted for reasons other than IPT were also reviewed, to compare the normal anatomy of the corpora cavernosa with that of IPT patients.Twenty-nine IPT cases were identified, including the three described here. All patients presented with perineal pain and in all cases the thrombus was located in the proximal part of the corpora cavernosa.IPT has been associated with haematological diseases, drugs, prior priapism, sexual activity, bicycle riding and aeroplane flights. A fibrous septum within the corporeal tissue has been identified with advanced imaging modalities. Ultrasound, computed tomography and MRI have proven useful in the diagnosis. Both surgical and medical treatments have been attempted and the results have usually been good. However, two cases of surgical treatment have resulted in erectile dysfunction. It is suggested that ITP is based on the development of penile thrombosis and/or priapism in the presence of a pre-existing fibrous septum in the corpora cavernosa. MRI should be used to confirm the presence of a thrombus and a septum. First choice of treatment is pain medication and systemic anticoagulation; more invasive treatments should only be attempted only if this approach fails.

show abstract

“…In the remaining 10 cases the issue was not addressed and the images of the condition were unclear with regard to a septum [1][2][3][11][12][13]21,22].…”

Section: Literature Reviewmentioning

confidence: 99%

Section: Literature Reviewmentioning

confidence: 99%

Idiopathic partial thrombosis of the corpus cavernosum: Aetiology, diagnosis and treatment

Hulth¹,

Albersen

Fode³

et al. 2012

Scandinavian Journal of Urology

View full text Add to dashboard Cite

show abstract

“…14,15 There is also a third case of tamsulosin associated with partial priapism, in which a proximal corpora thrombosis was identified. 8 The case we report is the fourth published. In a recent multicenter trial conducted to study the influence of the drug on sexual function, daily tamsulosin (0.4 mg) was compared with placebo and alfuzosin (7.5 mg), but priapism did not occur in any of the groups, substantiating the low incidence of this adverse event.…”

Section: Discussionmentioning

confidence: 82%

“…The first report dates to 1979 and the last to 2009. 7,8 The selected articles were analyzed, and a table was created summarizing patient characteristics, type of drug, dosage, management and clinical outcome of each one (Table 1).…”

Section: Resultsmentioning

confidence: 99%

Adrenergic α-blockers: an infrequent and overlooked cause of priapism

et al. 2011

View full text Add to dashboard Cite

A systematic review of the literature about the causal relationship between priapism and adrenergic a-blockers used for the treatment of lower urinary tract symptoms (LUTS) and arterial hypertension was accomplished. While opportunely describing a case of tamsulosin-induced priapism, we reviewed the literature using MEDLINE, COCHRANE and LILACS libraries, selecting all the articles until the present time addressing the association between priapism and a-blockers. Our patient was a healthy 32-year-old man who reported LUTS. His prostate was firm and moderately enlarged on digital rectal examination, measuring 30 grams on transabdominal ultrasound. Empirical treatment with tamsulosin was initiated and he developed priapism the day after the first dose of the drug. Erection was reverted by aspiration of the corpora and intracavernosal injection of adrenaline. Despite the late presentation (40 h of erection), he had no ED on follow-up. In the systematic review, among 2157 articles on priapism, only 13 similar cases reported a-blockers as the etiology of priapism. Therefore, adrenergic a-blockers are effective and safe drugs, with few serious adverse reactions. Nevertheless the association with priapism is well documented and related to substantial morbidity, this is an infrequent event and should not preclude their use, considering that the patient be sufficiently informed.

show abstract

“…Toch lijkt het ontstaan meestal idiopathisch [1][2][3][4][5][6][7][8][9][10][11]. Wel verdient het aanbeveling om hematologische tests te verrichten of de patiënt voor dergelijke tests door te verwijzen naar de hematoloog.…”

Section: Discussieunclassified

Case report. Het herkennen en behandelen van een idiopathische partiële trombose van het corpus cavernosum, een zeldzaam en wellicht onbekend fenomeen in de acute urologie

Jongerius¹,

Selm

Beck

2017

Tijdschr Urol

View full text Add to dashboard Cite

show abstract

Partial priapism secondary to tamsulosin: a case report and review of the literature

Cited by 28 publications

References 14 publications

Idiopathic partial thrombosis of the corpus cavernosum: Aetiology, diagnosis and treatment

Idiopathic partial thrombosis of the corpus cavernosum: Aetiology, diagnosis and treatment

Adrenergic α-blockers: an infrequent and overlooked cause of priapism

Case report. Het herkennen en behandelen van een idiopathische partiële trombose van het corpus cavernosum, een zeldzaam en wellicht onbekend fenomeen in de acute urologie

Contact Info

Product

Resources

About