The work is devoted to the experimental and numerical study of the dynamics and destruction of water droplets in the air flow behind incident shock wave in the Weber number range We = 150-2350. The structure of the flow near and in the wake of the drop is studied, the streamline features are established that determine the type of evolution of the drop form characteristic of these breakup modes and the erosion character. Comparison of the results of numerical simulation with experiments on the morphology of the drop was performed, as well as on dynamics, deformation, and the induction delay of breakup. Good agreement between calculations and experiments on the main characteristics of the process is shown.