Particle separation by standing surface acoustic waves inside a sessile droplet

Han, Junlong; Hu, Hong; Huang, Qing; Lei, Yu Lin

doi:10.1016/j.sna.2021.112731

Cited by 24 publications

(8 citation statements)

References 51 publications

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“…However, sample detection requires only one drop or less in most testing cases [ 9 ], and also the addition of microchannels, catheters and injection pumps can make the detection system complex and difficult to carry, the difficulty of operation and detection time will also increase at the same time [ 10 ]. Another simpler and more ingenious miniaturization system consists of a piezoelectric substrate and a fixed droplet placed directly on a piezoelectric platform [ 11 ]. It avoids the complicated fabrication and bonding process of the microfluidic channel, and requires no additional equipment, such as external pump sources and so on [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Enhanced Detection in Droplet Microfluidics by Acoustic Vortex Modulation of Particle Rings and Particle Clusters via Asymmetric Propagation of Surface Acoustic Waves

Liu

et al. 2022

Biosensors

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As a basis for biometric and chemical analysis, issues of how to dilute or concentrate substances such as particles or cells to specific concentrations have long been of interest to researchers. In this study, travelling surface acoustic wave (TSAW)-based devices with three frequencies (99.1, 48.8, 20.4 MHz) have been used to capture the suspended Polystyrene (PS) microspheres of various sizes (5, 20, 40 μm) in sessile droplets, which are controlled by acoustic field-induced fluid vortex (acoustic vortex) and aggregate into clusters or rings with particles. These phenomena can be explained by the interaction of three forces, which are drag force caused by ASF, ARF caused by Leaky-SAW and varying centrifugal force. Eventually, a novel approach of free transition between the particle ring and cluster was approached via modulating the acoustic amplitude of TSAW. By this method, multilayer particles agglomerate with 20 μm wrapped around 40 μm and 20 μm wrapped around 5 μm can be obtained, which provides the possibility to dilute or concentrate the particles to a specific concentration.

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Section: Introductionmentioning

confidence: 99%

Enhanced Detection in Droplet Microfluidics by Acoustic Vortex Modulation of Particle Rings and Particle Clusters via Asymmetric Propagation of Surface Acoustic Waves

Liu

et al. 2022

Biosensors

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“…An SSAW-based technology for particle separation inside a sessile droplet was demonstrated. 99 As can be seen from Fig. 10, the SSAW method is adopted in this paper to separate microparticles by dynamically adjusting the contact angle of the droplets, which can significantly change the position distribution of particles in droplets, thus achieving particle separation in a mixed solution.…”

Section: Ssaws Driven Manipulationmentioning

confidence: 99%

Surface acoustic wave manipulation of bioparticles

Dang

Yang

et al. 2023

Soft Matter

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“…SAWs are known for leaking 28 radiative energy into the surrounding uid, while simultaneously inducing strong localized streaming phenomena. By adding a small volume of particle-laden liquid in a microwell or as a sessile droplet on top of the path of the propagating SAW, different mixing, aggregation, and particle clustering can occur [29][30][31][32][33][34] . Furthermore, the intensity of the streaming can be such that a small droplet can be displaced using SAWs [35][36][37] .…”

Section: Introductionmentioning

confidence: 99%

Cavity-Agnostic Acoustofluidic Functions Enabled by Guided Flexural Waves on a Membrane Acoustic Waveguide Actuator

Vachon,

Merugu,

Sharma

et al. 2023

Preprint

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This article presents an in-depth exploration of the acoustofluidic capabilities of guided flexural waves (GFWs) generated by a membrane acoustic waveguide actuator (MAWA). By harnessing the potential of GFWs, cavity-agnostic advanced particle manipulation functions are achieved, unlocking new avenues for microfluidic systems and lab-on-a-chip development. The localized acoustofluidic effects of GFWs arising from the evanescent nature of the acoustic fields they induce inside a liquid medium are numerically investigated to highlight their unique and promising characteristics. Unlike traditional acoustofluidic technologies, the GFWs propagating on the MAWA’s membrane waveguide allow for cavity-agnostic particle manipulation, irrespective of the resonant properties of the fluidic chamber. Moreover, the acoustofluidic functions enabled by the device depend on the flexural mode populating the active region of the membrane waveguide. Experimental demonstrations using two types of particles include in-sessile-droplet particle transport, mixing, and spatial separation based on particle diameter, along with streaming-induced counter-flow virtual channel generation in microfluidic PDMS channels. These experiments emphasize the versatility and potential applications of the MAWA as a microfluidic platform targeted at lab-on-a-chip development and showcase the MAWA’s compatibility with existing microfluidics systems.

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Particle separation by standing surface acoustic waves inside a sessile droplet

Cited by 24 publications

References 51 publications

Enhanced Detection in Droplet Microfluidics by Acoustic Vortex Modulation of Particle Rings and Particle Clusters via Asymmetric Propagation of Surface Acoustic Waves

Enhanced Detection in Droplet Microfluidics by Acoustic Vortex Modulation of Particle Rings and Particle Clusters via Asymmetric Propagation of Surface Acoustic Waves

Surface acoustic wave manipulation of bioparticles

Cavity-Agnostic Acoustofluidic Functions Enabled by Guided Flexural Waves on a Membrane Acoustic Waveguide Actuator

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