Particle separation efficiency in two 10-mm hydrocyclones in series

Hwang, Kuo‐Jen; Lyu, Sin-Yi; Nagase, Yoichi

doi:10.1016/j.jtice.2008.08.006

Cited by 25 publications

(10 citation statements)

References 10 publications

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“…The observed onset of separation for the design A devices was 20 mL min −1 , corresponding to a Reynolds number of Re = 283 with respect to the hydrocyclone chamber diameter. This stands in contrast to commercial centimeter‐scale hydrocyclones, where operational Re values typically vary from a few thousand to several tens of thousands 51,55,60,63. The significantly lower Re flows used in our 1.5 mm μHC devices demonstrate that the same separation principle can be applied even under laminar conditions.…”

Section: Resultsmentioning

confidence: 87%

“…The potential for miniaturized hydrocyclones for high throughput separations in clinical and biological applications has long been considered. [9,62] The smallest commercially available hydrocyclone has a main chamber diameters of 10 mm, [51,53,55,63] and recent studies have explored hydrocyclone designs below 5 mm scale. [57][58][59]64] Bhardwaj et al reported a 350 μm hydrocyclone fabricated by conventional thermoplastic micromachining.…”

Section: Hydrocyclone Scalingmentioning

confidence: 99%

See 1 more Smart Citation

Miniaturization of Hydrocyclones by High‐Resolution 3D Printing for Rapid Microparticle Separation

Han

Krasniqi

Kim

et al. 2020

Adv Materials Technologies

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principles of operation. [10][11][12] However, the effective separation of micron-scale components from biological matrices using these conventional techniques is often constrained by low throughput, biofouling, and incompatibility with the need for continuous and automated processing. [3,6,7,9] In addition, biological particles such as cells are often susceptible to damage or degradation due to the application of high forces during centrifugal or membrane based separations, presenting a further obstacle to achieving time-and cost-effective isolation of biological targets. [3,[13][14][15][16][17][18] Microfluidic-based separations based on both active and passive techniques have been investigated as promising approaches to continuous-flow isolation of micron-scale particles from fluid suspensions. Active separation methods utilize external forces including electric, [19] magnetic, [20] and acoustic forces, [21] whereas passive separation methods utilize hydrodynamic forces induced by microstructure-fluid interactions and fluid dynamic phenomena. [22][23][24] Passive separations are particularly attractive as they do not require external actuation beyond the application of bulk fluid flow through the system, thereby minimizing instrumentation requirements and system complexity. Microfluidic filtration is a straightforward strategy for particle separation utilizing sizebased retention, with an integrated membrane, micropillar array, or other porous structure able to selectively pass particles smaller than the pore size while retaining other larger particles. [25][26][27] However, as with its macroscale counterpart, filtration presents inherent challenges when handling large sample volumes, including membrane biofouling, limited throughput, high pressure requirements, and limited scaling. [26,[28][29][30] While passive hydrodynamic separation techniques such as inertial focusing, [24,31] deterministic lateral displacement, [32,33] pinched flow fractionation, [34] and Dean flow focusing [22,35,36] can overcome these constraints and are well suited to continuous flow operation, throughput remains fundamentally limited since relatively low Reynolds number flows must be employed in these systems to maintain force balance during microfluidic separations. [23,30,37] At the macroscale, hydrocyclone technology has evolved as a powerful and simple solid-liquid separation technology traditionally used in large-volume industrial processes including mineral dewatering [38,39] and desliming, [40] heavy metal recovery, [41,42] and water treatment. [43][44][45] Hydrocyclones enable Hydrocyclones are a simple and powerful particle separation technology, widely used in macroscale industrial processes, with enormous potential for miniaturization. Although recent efforts to shrink hydrocyclones to the centimeter scale have shown great promise for passive and high-throughput microparticle separations, further miniaturization is constrained by limited understanding of the impact of device size scale and design on separation performance,...

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Section: Resultsmentioning

confidence: 87%

Section: Hydrocyclone Scalingmentioning

confidence: 99%

Miniaturization of Hydrocyclones by High‐Resolution 3D Printing for Rapid Microparticle Separation

Han

Krasniqi

Kim

et al. 2020

Adv Materials Technologies

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show abstract

“…Among the classifying equipment [1,2] currently available, hydrocyclones are one of the most popular pieces of equipment [3,4,5] and can be applied in minering [6] and bio-engineering [7,8] processes and slurry treatment [9] (an emerging field). Based on previous studies, hydrocyclones have proven to be universal devices with various advantages such as its compact size, no moving parts, simple and inexpensive manufacturing, and minimal maintenance.…”

Section: Introductionmentioning

confidence: 99%

Three Output Membrane Hydrocyclone: Classification and Filtration

Lin

2019

Molecules

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In this study, through simulation and experimental verification, we proposed a novel hydrocyclone in which a tubular ceramic membrane passed through the overflow outlet to the underflow outlet. The centers of overflow and underflow outlets were tubular membranes equipped with an exit of outside-in filtration, and the overflow the underflow outlets were shaped into annular (donut shape) exits. Thus, this novel hydrocyclone has three outlets, namely the overflow dilute liquid, the underflow concentrated liquid, and clear filtrate. This system enabled higher dilution of hydrocyclone overflow concentration than that in the traditional system. Furthermore, underflow was more concentrated, and we obtained a clear filtrate. Therefore, this device can simultaneously perform classification and filtration, which is valuable for special liquid recycling. For instance, in wafer cutting fluid recovery in solar energy processes, the fluid with more silicon can function as the overflow, the fluid with more silicon carbide can function as the underflow, and the polyethylene glycol (PEG) organic solvent can function as the clear filtrate.

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“…Hydrocyclone is a favorable classifying equipment for its separation of solids [1][2][3]. And it is also a popular device in that it is compact, easy and inexpensive to manufacture, contains no moving parts and requires very little maintenance [4][5][6], etc.…”

Section: Introductionmentioning

confidence: 99%

Experimental and simulation of a novel hydrocyclone-tubular membrane as overflow pipe

Wang

2018

Separation and Purification Technology

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Particle separation efficiency in two 10-mm hydrocyclones in series

Cited by 25 publications

References 10 publications

Miniaturization of Hydrocyclones by High‐Resolution 3D Printing for Rapid Microparticle Separation

Miniaturization of Hydrocyclones by High‐Resolution 3D Printing for Rapid Microparticle Separation

Three Output Membrane Hydrocyclone: Classification and Filtration

Experimental and simulation of a novel hydrocyclone-tubular membrane as overflow pipe

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