Parvovirus B19–Associated Arthritis

Tello-Winniczuk, Nina; Díaz-Jouanen, E; Díaz-Borjón, Alejandro

doi:10.1097/rhu.0b013e31823abf1a

Cited by 7 publications

(1 citation statement)

References 12 publications

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“…The virus is globally distributed and most healthy adults are seropositive. While outbreaks of parvovirus are uncommon they have been reported 7. Many cases of parvovirus B19 are asymptomatic but the virus is also responsible for a wide spectrum of clinical manifestations, including erythema infectiosum, aplastic anaemia and an acute arthritis.…”

Section: Causative Organismsmentioning

confidence: 99%

Viral arthritis

Marks

2016

Clinical Medicine

132

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Acute-onset arthritis is a common clinical problem facing both the general clinician and the rheumatologist. A viral aetiology is though to be responsible for approximately 1% of all cases of acute arthritis with a wide range of causal agents recognised. The epidemiology of acute viral arthritis continues to evolve, with some aetiologies, such as rubella, becoming less common due to vaccination, while some vector-borne viruses have become more widespread. A travel history therefore forms an important part of the assessment of patients presenting with an acute arthritis. Worldwide, parvovirus B19, hepatitis B and C, HIV and the alphaviruses are among the most important causes of virally mediated arthritis. Targeted serological testing may be of value in establishing a diagnosis, and clinicians must also be aware that low-titre autoantibodies, such as rheumatoid factor and antinuclear antibody, can occur in the context of acute viral arthritis. A careful consideration of epidemiological, clinical and serological features is therefore required to guide clinicians in making diagnostic and treatment decisions. While most virally mediated arthritides are self-limiting some warrant the initiation of specific antiviral therapy.

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Section: Causative Organismsmentioning

confidence: 99%