Past Present and Future Status of HIV-AIDS Pandemic Problem in World

Chopra, Narendra Kumar; Han, Ni; Lim, Vichard

doi:10.33425/2639-9458.1050

Cited by 10 publications

(4 citation statements)

References 13 publications

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“…Globally, less than 30% of women of reproductive age have an in-depth knowledge of HIV/ AIDS [8]. African women have also limited knowledge, attitude, and behaviour regarding how HIV is transmitted, the repercussions of infection, and methods of prevention [9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Spatial variation and predictors of composite index of HIV/AIDS knowledge, attitude and behaviours among Ethiopian women: A spatial and multilevel analyses of the 2016 Demographic Health Survey

Habte,

Bizuayehu,

Haile

et al. 2024

PLoS ONE

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Background Although the dissemination of health information is one of the pillars of HIV prevention efforts in Ethiopia, a large segment of women in the country still lack adequate HIV/AIDS knowledge, attitude, and behaviours. Despite many studies being conducted in Ethiopia, they mostly focus on the level of women’s knowledge about HIV/AIDS, failing to examine composite index of knowledge, attitude, and behaviour (KAB) domains comprehensively. In addition, the previous studies overlooked individual and community-level, and spatial predictors. Hence, this study aimed to estimate the prevalence, geographical variation (Hotspots), spatial predictors, and multilevel correlates of inadequate HIV/AIDS-Knowledge, Attitude, and Behaviour (HIV/AIDS-KAB) among Ethiopian women. Methods The study conducted using the 2016 Ethiopian Demographic and Health Survey data, included 12,672 women of reproductive age group (15–49 years). A stratified, two-stage cluster sampling technique was used; a random selection of enumeration areas (clusters) followed by selecting households per cluster. Composite index of HIV/AIDS-KAB was assessed using 11 items encompassing HIV/AIDS prevention, transmission, and misconceptions. Spatial analysis was carried out using Arc-GIS version 10.7 and SaTScan version 9.6 statistical software. Spatial autocorrelation (Moran’s I) was used to determine the non-randomness of the spatial variation in inadequate knowledge about HIV/AIDS. Multilevel multivariable logistic regression was performed, with the measure of association reported using adjusted odds ratio (AOR) with its corresponding 95% CI. Results The prevalence of inadequate HIV/AIDS-KAB among Ethiopian women was 48.9% (95% CI: 48.1, 49.8), with significant spatial variations across regions (global Moran’s I = 0.64, p<0.001). Ten most likely significant SaTScan clusters were identified with a high proportion of women with inadequate KAB. Somali and most parts of Afar regions were identified as hot spots for women with inadequate HIV/AIDS-KAB. Higher odds of inadequate HIV/AIDS-KAB was observed among women living in the poorest wealth quintile (AOR = 1.63; 95% CI: 1.21, 2.18), rural residents (AOR = 1.62; 95% CI: 1.18, 2.22), having no formal education (AOR = 2.66; 95% CI: 2.04, 3.48), non-autonomous (AOR = 1.71; 95% CI: (1.43, 2.28), never listen to radio (AOR = 1.56; 95% CI: (1.02, 2.39), never watched television (AOR = 1.50; 95% CI: 1.17, 1.92), not having a mobile phone (AOR = 1.45; 95% CI: 1.27, 1.88), and not visiting health facilities (AOR = 1.46; 95% CI: 1.28, 1.72). Conclusion The level of inadequate HIV/AIDS-KAB in Ethiopia was high, with significant spatial variation across regions, and Somali, and Afar regions contributed much to this high prevalence. Thus, the government should work on integrating HIV/AIDS education and prevention efforts with existing reproductive health services, regular monitoring and evaluation, and collaboration and partnership to tackle this gap. Stakeholders in the health sector should strengthen their efforts to provide tailored health education, and information campaigns with an emphasis on women who lack formal education, live in rural areas, and poorest wealth quintile should be key measures to enhancing knowledge. enhanced effort is needed to increase women’s autonomy to empower women to access HIV/AIDS information. The media agencies could prioritise the dissemination of culturally sensitive HIV/AIDS information to women of reproductive age. The identified hot spots with relatively poor knowledge of HIV/AIDS should be targeted during resource allocation and interventions.

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Section: Introductionmentioning

confidence: 99%

Spatial variation and predictors of composite index of HIV/AIDS knowledge, attitude and behaviours among Ethiopian women: A spatial and multilevel analyses of the 2016 Demographic Health Survey

Habte,

Bizuayehu,

Haile

et al. 2024

PLoS ONE

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“…В развитии эпидемии ВИЧ-инфекции важную роль придают половому пути инфицирования. По данным литературы, всего 40-80% случаев заражения ВИЧ-инфекцией в мире связаны с реализацией полового пути передачи возбудителя [3].…”

Section: Introductionunclassified

Sentinel Epidemiological Surveillance of HIV infection among Pregnant Women in the Republic of Karakalpakstan

Kalniyazova,

Matnazarova,

Mirtazayev

2023

JHD

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HIV/AIDS remains one of the major global public health concerns of today. In low-income countries, HIV/AIDS remains among the top three leading causes of death for women of childbearing age.The purpose of the study: to evaluate the indicators of the sentinel epidemiological control service for HIV infection among pregnant women in the Republic of Karakalpakstan.Methods. We studied the indicators of the sentinel epidemiological control service for HIV-infected and pregnant women in the Republic of Karakalpakstan for 2011-2021.Results. The highest rate of long-term incidence of HIV-infected women was recorded from 2015 to 2020. Between 2011 and 2021, 440,236 pregnant women were tested for HIV, with the incidence being high in 2014-2016. In 2011, the level of HIV/AIDS infection was 13.4 per 100,000 population, while in 2013 it was 14.1, in 2016 it was 12.5. And by 2021, the number of HIV-infected women will increase again. It has been established that the incidence of HIV infection among women, including pregnant women, varies from year to year. Also, when analyzing the incidence of HIV in the regions, it was found that the incidence in the regions is not the same.Conclusions. In the Republic of Karakalpakstan, HIV infection is more often detected among women, and it has been established that the mode of transmission is sexual. According to social status, it is noted more among the rural population, a predisposition to the disease among young people of reproductive age, epidemiological characteristics and criteria for antiretroviral therapy are recommended.Key words: HIV/AIDS, prevalence, pregnant women, reproductive age, sexual partner, risk group.

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“…HIV-1 contributes to cancer development directly through oncogenic effects of HIV proteins, such as Trans -activator of transcription (Tat) and indirectly through immunosuppression and promiting coinfections by other oncogenic viruses [ [5] , [6] , [7] , [8] ]. HIV was discovered in 1983 as the aetiological cause of acquired immunodeficiency syndrome (AIDS), which is a global pandemic that continues to devastate many communities, worldwide [ 9 ]. As of 2017, there were 36.9 million people living with HIV, globally [ 10 ] with the majority of these infections occurring in the resource-limited countries, especially those in the sub-Saharan Africa [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Long noncoding RNAs (lncRNAs) in HIV-mediated carcinogenesis: Role in cell homeostasis, cell survival processes and drug resistance

Makgoo

Mosebi

Mbita

2022

Non-coding RNA Research

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Past Present and Future Status of HIV-AIDS Pandemic Problem in World

Cited by 10 publications

References 13 publications

Spatial variation and predictors of composite index of HIV/AIDS knowledge, attitude and behaviours among Ethiopian women: A spatial and multilevel analyses of the 2016 Demographic Health Survey

Spatial variation and predictors of composite index of HIV/AIDS knowledge, attitude and behaviours among Ethiopian women: A spatial and multilevel analyses of the 2016 Demographic Health Survey

Sentinel Epidemiological Surveillance of HIV infection among Pregnant Women in the Republic of Karakalpakstan

Long noncoding RNAs (lncRNAs) in HIV-mediated carcinogenesis: Role in cell homeostasis, cell survival processes and drug resistance

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