Patch repair for congenital diaphragmatic hernia: is it really a problem?

Tsai, Jacqueline; Sulkowski, Jason P.; Adzick, N. Scott; Hedrick, Holly L.; Flake, Alan W.

doi:10.1016/j.jpedsurg.2011.11.054

Cited by 87 publications

(77 citation statements)

References 20 publications

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“…24 Experience from "high-volume" CDH programs in Philadelphia, USA, and Liverpool, UK, has been strikingly different with recent studies from these centres showing very low rates of patch failure ( o 10%) using GORE-TEX. 18,25 We (like others) strongly believe that patch failure reflects a technical problem with its implantation at the primary CDH operation by the surgeon. 18,25 Minimally invasive techniques (MIS) have become available for diaphragm repair.…”

Section: Stabilisationmentioning

confidence: 90%

“…18,25 We (like others) strongly believe that patch failure reflects a technical problem with its implantation at the primary CDH operation by the surgeon. 18,25 Minimally invasive techniques (MIS) have become available for diaphragm repair. Benefits potentially include reduced postoperative pain and improved cosmesis whilst physiological derangement(s) during operation may be hazardous in fragile newborns.…”

Section: Stabilisationmentioning

confidence: 90%

“…Technical factors with prosthetic implantation likely equate with early patch disruption and recurrent herniation. 18,25 Reported outcome(s) and long-term follow-up…”

Section: Morbiditymentioning

confidence: 99%

See 2 more Smart Citations

Congenital diaphragmatic hernia: Where and what is the evidence?

Losty

2014

Seminars in Pediatric Surgery

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Section: Stabilisationmentioning

confidence: 90%

Section: Stabilisationmentioning

confidence: 90%

See 1 more Smart Citation

Congenital diaphragmatic hernia: Where and what is the evidence?

Losty

2014

Seminars in Pediatric Surgery

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“…Fauza 57 , em artigo de revisão, comenta a retirada das mesmas células de humanos e a implantação em uma matriz acelular construindo um "músculo diafragma" a partir das próprias células do paciente. Evidentemente, isso não é uma prática corriqueira, uma vez que o Food and Drug Administration (FDA) ainda não permite sua utilização, mas é possível construir um tendão muscular diafragmá-tico autólogo, sem a necessidade de colocar uma prótese nas situações graves quando não existe diafragma 57 , visto que o uso de próteses pode levar a uma taxa de recidiva da hérnia de até 50% 58 .…”

Section: Perspectivasunclassified

Manejo pré-natal da hérnia diafragmática congênita: presente, passado e futuro

Gallindo

Gonçalves

Figueira

et al. 2015

Rev. Bras. Ginecol. Obstet.

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Manejo pré-natal da hérnia diafragmática congênita: presente, passado e futuro ResumoA hérnia diafragmática congênita é um defeito de formação do diafragma que acomete entre 1:2.000 e 1:4.000 nascidos vivos e constitui 8% das principais anomalias congênitas. Avanços médicos nos últimos 30 anos envolvendo diagnóstico pré-natal, intervenção fetal, manejo clinico e cirúrgico neonatal têm mudado a sobrevivência dos seus portadores. A evolução histórica desses avanços ajuda a compreender o esforço na busca de melhores resultados desse defeito muitas vezes fatal. Perspectivas na utilização de bioengenharia e terapia envolvendo células tronco podem trazer novas esperanças para os fetos com hérnia diafragmática congênita. AbstractThe congenital diaphragmatic hernia is a defect in the formation of the diaphragm, which affects between 1:2,000 and 1:4,000 live births and represents 8% of major congenital anomalies. Medical advances in the last 30 years involving prenatal diagnosis, fetal intervention, neonatal surgical and clinical management have changed the survival of these patients. The historical evolution of these advances helps us to understand the effort in pursuit of better results of this defect, which is often lethal. Perspectives on the use of bioengineering and therapy involving stem cells may bring new hope for fetuses with congenital diaphragmatic hernia.

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“…Patch materials commonly applied include polytetrafluoroethylene (PTFE) 1 and small intestinal submucosa (SIS), derived from decellularised porcine submucosa. 2 Both types of materials have been found successful in some studies, [3][4][5] but showed high recurrence rates in others. 2,6,7 A recent meta-analysis reported no differences between PTFE and SIS, both materials having a recurrence rate of over 30%.…”

Section: Introductionmentioning

confidence: 99%