Patch test results with fragrance markers of the baseline series – analysis of the European Surveillance System on Contact Allergies (ESSCA) network 2009–2012

Abstract

Contact allergy to fragrances is common throughout Europe, with regional variation probably being explained by patch test technique, and differences in exposure and referral patterns. The current basic markers of fragrance sensitivity in the baseline series should be supplemented with additional fragrance allergens.

Sensitization to, and allergic contact dermatitis caused by, colophonium in north‐eastern Italy in 1996 to 2016 with a focus on occupational exposures

“…The overall average prevalence of colophonium sensitization in this time frame was 1.67%. On comparison of our results with those of other European studies, such as the European Surveillance System on Contact Allergies (ESSCA) results presented by Frosch et al, we confirm a low prevalence of sensitization to this allergen in Italy. In the ESSCA study, colophonium sensitization prevalence showed marked differences between the 12 European countries that participated in the study.…”

Thoughts on how to improve the quality of multicentre patch test studies

“…They differ concerning shape (round or square), material (aluminium or plastics), and the use of filter paper. Investigations have, on the whole, shown good agreement between various systems , but there are differences , which is why the same system, whether it is a preloaded or initially unloaded system, should preferably be used for the same sensitizers when an MPTS is performed. Thus, some sensitizers within an MPTS can be tested with a preloaded system, and other sensitizers can be tested with an unloaded system.…”

Contact allergy to ingredients of topical medications: results of the European Surveillance System on Contact Allergies (ESSCA), 2009–2012

“…Besides the substances considered here, other excipients may act as haptens, namely preservatives and fragrances. Results with these have been published elsewhere (A. Giménez Arnau, in preparation, and Frosch, Johansen and Schuttelaar).…”