Patho-physiological evaluation of Duranta erecta for the treatment of urolithiasis

Agawane, Sachin B.; Gupta, Vidya S.; Kulkarni, Mahesh J.; Bhattacharya, Asish K.; Koratkar, Santosh S.; Rao, Vamkudoth Koteswara

doi:10.1016/j.jaim.2017.08.001

Cited by 20 publications

(11 citation statements)

References 10 publications

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“…The methanol extract of D. erecta (L) leaves that were collected from CSIR-National Chemical Laboratory Colony, Pune, indicated the presence of secondary metabolites such as glycoside, saponins, sterols, flavonoids, phenols, tannins, alkaloids, carbohydrates, and proteins [25]. The aqueous extract of D. erecta fresh leaves was collected from the residential quarters within the University of Nigeria, Nsukka, indicated small quantities (+) of alkaloids, flavonoids, tannins, anthraquinone, and glycosides in the extract, while saponins were moderately present (++), steroids were conspicuously absent [26].…”

Section: Resultsmentioning

confidence: 99%

The Phytochemical Screening Hexane and Methanol Extract of Sinyo Nakal (Duranta Repens)

Sugita

Amilia

Budi

et al. 2020

Asian J Pharm Clin Res

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Objective: Phytochemicals are naturally present in every part of plants range from leaves, stem bark, and fruits to roots. The use of plant-based medicine is popular among individuals and communities in developing countries. This study evaluated that the phytochemical profile of Duranta repens fruits was collected from Jombang, East Java, Indonesia. Methods: Air-dried D. repens fruits were macerated by n-hexane and methanol, a separate flask. n-Hexane extract, then underwent saponification to remove fat. Then, the unsaponifiable of n-hexane and methanol extract was tested through phytochemical screening, respectively. Results: The methanol extract showed the presence of alkaloids, flavonoids, tannins, and steroids, but the unsaponifiable fraction only contained steroids. The unsaponifiable fraction was found to be a mixture of hydrocarbons ranging from C13-C20, fatty acids (palmitic and linoleic acid), squalene, and Vitamin E. Conclusion: The phytochemical screening of the plant plays an important role for pharmaceutical studies especially discovering new potential drugs for the treatment of various diseases.

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Section: Resultsmentioning

confidence: 99%

The Phytochemical Screening Hexane and Methanol Extract of Sinyo Nakal (Duranta Repens)

Sugita

Amilia

Budi

et al. 2020

Asian J Pharm Clin Res

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“…15 The methanol leaf extract was shown to have antifungal activity and antiurolithiatic effects. 16 , 17 The methanol ripe fruit extract did not show significant anthelmintic effects. 14 Oral evidence from some traditional healers in the Igbo speaking part of Eastern Nigeria suggests the effectiveness of infusion of ripe fruits in the management of DM.…”

Section: Introductionmentioning

confidence: 94%

Anti-hyperglycemic and anti-dyslipidemic activities of methanol ripe fruit extract of Duranta erecta L (Verbenaceae) in normoglycemic and hyperglycemic rats

Eke

Okpara

2021

Journal of Traditional and Complementary Medicine

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“…Different treatment options are available to remove calculi, such as surgical removal, lithotripsy and laparoscopy. Despite the higher treatment costs, these techniques may produce a risk of causing acute renal injury, which decreases renal function and also recurrence of calculi observed in some cases with a possible recurrence rate of 10%, 33% and 50% at 1st, 5th and 10th year respectively (5). Costly diagnostic and treatment procedures for the therapeutic management of patients require better adequate alternative therapies.…”

Section: Introductionmentioning

confidence: 99%

Herbal remedies used for the management of urolithiasis in Abbottabad, Northern Pakistan

et al. 2021

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The current study was performed to evaluate the ethnobotanical uses of medicinal plants to treat and prevent kidney diseases, especially urolithiasis in the Abbottabad region, Northern Pakistan. Field surveys were conducted from 2014–2016 in various rural and tribally dwelled hilly areas like Ayubia National Park, Sherwan and Thandiani. Ethnobotanical information about the medicinal plants employed to treat urinary ailments was obtained from well-informed sources like local healers (hakims) and residents (men/women), who had vast knowledge of local plants uses. The questionnaire method was adopted to record the information and queries were made to verify the information. Informed consent was obtained from each informant before conducting the interview process. Quantitative ethnobotanical indices were calculated for each recorded species. Correlation analysis between the RFC, UV and FL% was tested by Pearson’s correlation, SPSS (ver. 16). A total of 38 plant species belonging to 27 families were being used in the study area to treat Urolithiasis or kidney stone diseases. Asteraceae was the most dominant family with 5 species. Local people used different methods of preparation for different plant parts; among them, decoction was the popular and dominant way of preparation (52.6%), followed by powder (18.4%), extracts (15.7%), juice (7.8%) and cooked (5.2%). The highest UV was recorded for Rumex acetosa L. (1.14) followed by Agrimonia eupatoria L. (1.1), Equisetum ramosissimum Desf. (1.05), Aerva lanata L. (1.04), Eclipta alba Hassak. (1.03). Moreover, twenty-three species were recoded with above 50% Fidelity level. It was found that most of the plant species (16 species) were explicitly used to remove kidney stones. All the obtained data about the ethnomedicinal uses of plants to treat urinary tract ailments are alphabetically categorized to their botanical name/family, local name, phytoconstituents, dosage and route of administration, along with quantitative indices value. All the collected ethnomedicinal plants require a thorough scientific investigation for isolation, identification, biochemical assays, toxicities and evaluation of pharmacological activities of the phytoconstituents, especially of the plants recorded with a high-fidelity level before their usage in clinics.

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Patho-physiological evaluation of Duranta erecta for the treatment of urolithiasis

Cited by 20 publications

References 10 publications

The Phytochemical Screening Hexane and Methanol Extract of Sinyo Nakal (Duranta Repens)

The Phytochemical Screening Hexane and Methanol Extract of Sinyo Nakal (Duranta Repens)

Anti-hyperglycemic and anti-dyslipidemic activities of methanol ripe fruit extract of Duranta erecta L (Verbenaceae) in normoglycemic and hyperglycemic rats

Herbal remedies used for the management of urolithiasis in Abbottabad, Northern Pakistan

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