Pathogenesis and treatment of anemia in inflammatory bowel disease

Is Iron Deficiency in the Absence of Anemia Associated With Fatigue in Inflammatory Bowel Disease?

“….It has been reported to be strongly associated with fatigue in cancer (13,14) as well as in IBD (9,10,15), although findings are not consistent (5). The anemia common to patients with IBD is mainly due to iron deficiency from blood loss, either alone or in combination, and suppression of erythropoiesis and iron binding (17,18) due to proinflammatory cytokine activity. There has been support for aggressively treating anemia in IBD using iron therapy for those who are iron deficient and using erythropoietin for subjects with impaired red blood cell production (15,(18)(19)(20).…”

Gastrointestinal B-lymphoblastic lymphoma in a dog: a case report

“…Anaemia is typically normocytic normochromic. It was assumed in this case of microcytic hypochromic anaemia that pre-existing anaemia of iron deficiency and anaemia of inflammation could be present due to inflammatory bowel disease (Weiss and Gasche 2010) and that these conditions were subsequently worsened by lymphoma. Lymphoma patients without bone marrow infiltration (which was not examined) may have anaemia of inflammation due to excessive release of cytokines such as IL-6 (Tisi et al 2014).…”

Algorithmus zur Diagnose von Eisenmangelanämie

“…Ein wichtiger Grund dafür ist, dass Ferritin, als Akute-PhaseProtein, bei Entzündungsprozessen erhöht ist. Dementsprechend sind die Grenzwerte bei chronischen Erkrankungen wie CED (<100 ng/ml) [38], chronischer Nierenkrankheit (<100 bis <200 ng/ml) [39] oder chronischer Herzinsuffizienz (<100 ng/mL oder <100-299 ng/mL mit TfS <20 %) [40] anders.…”