Pathogenesis of rheumatoid arthritis

Abstract

Insights in the pathogenesis of RA provide options to develop new therapeutic strategies aimed at the inhibition of pathogenetic relevant processes.

Grafting of Fibroblasts Isolated from the Synovial Membrane of Rheumatoid Arthritis (RA) Patients Induces Chronic Arthritis in SCID Mice—A Novel Model for Studying the Arthritogenic Role of RA Fibroblasts

“…The position of fibroblasts in the pathogenetic processes of RA is under discussion. T-cell and fibroblastfocused theories are mostly discussed as excluding theories, but present also some connecting points [8]. Figure 6.…”