Pathogenesis of various forms of infection in artificial hearts

Dobšák, Petr; Vasků, J; Jančík, Jiří; Eicher, Jean‐Christophe; Wotke, Jiří

doi:10.1016/s0928-4680(02)00082-2

Pathophysiology

2003

DOI: 10.1016/s0928-4680(02)00082-2

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Pathogenesis of various forms of infection in artificial hearts

Petr Dobšák¹,

J Vasků²,

Jiří Jančík³

et al.

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Cited by 3 publications

(2 citation statements)

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“…The analysis by electron microscopy showed more expressed lesions in liver and kidney than in the lung (20). Also, new procedures aimed to the specific stimulation of the mechanisms of immune defense in the TAH bearers were studied (21). Also, new procedures aimed to the specific stimulation of the mechanisms of immune defense in the TAH bearers were studied (21).…”

mentioning

confidence: 99%

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Czech Marathon in the Research of Heart Assist Systems and Total Artificial Heart

Vasků

2013

Artificial Organs

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mentioning

confidence: 99%

“…The study of the TAH infections enhanced the use of more specifically developed antibiotics focused exclusively to the slime biofilm protected bacteria on the diaphragm. Also, new procedures aimed to the specific stimulation of the mechanisms of immune defense in the TAH bearers were studied (21).…”

mentioning

confidence: 99%

Czech Marathon in the Research of Heart Assist Systems and Total Artificial Heart

Vasků

2013

Artificial Organs

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Maintenance of the internal environment in total artificial heart (TAH) recipients during long-term pumping

Vasků¹,

Dobšák

Wotke

2005

J Artif Organs

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Sixty-six long-term experiments were performed on animals (65 calves, 1 goat) after implantation with a total artificial heart (TAH). Animal survival ranged from 30 to 314 days using TAH devices ranging from the TNS-BRNO-II to the TNS-BRNO-VIIII. In these experiments some basic problems were studied which need to be overcome to achieve the optimal physiological status of the animal, the optimal maintenance of the internal environment, and the long-term survival of TAH recipients. The problem areas studied were: the vasomotor regulation of the periphery, the prevention of calcification of the driving diaphragms, the optimal regulation of homeostasis, and the pathogenesis and prevention of infection. The basic precondition for the experiments was the problem-free implantation of a TAH and the subsequent optimal method of postoperative care was investigated. By the gradual multifactorial solution of these individual problems, the prolongation of the survival period of experimental animals was achieved. The definite solution and elucidation of some complications during long-term survival is still an open problem because the multifactorial events that influence long-term TAH survival are often very complicated and can sometimes only be solved by overcoming numerous obstacles as a result of the deep functional interrelationships of the disorders present.

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In Vitro Formation of Biofilms on Lopez Enteral Feeding Valves: Implications for Critical Care Patients and Nurses

Solseng

Vinson

Gibbs

et al. 2008

Critical Care Nurse

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Pathogenesis of various forms of infection in artificial hearts

Cited by 3 publications

References 43 publications

Czech Marathon in the Research of Heart Assist Systems and Total Artificial Heart

Czech Marathon in the Research of Heart Assist Systems and Total Artificial Heart

Maintenance of the internal environment in total artificial heart (TAH) recipients during long-term pumping

In Vitro Formation of Biofilms on Lopez Enteral Feeding Valves: Implications for Critical Care Patients and Nurses

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