Pathologic Correlation of Gallstones

Kozoll, Donald D.; Dwyer, George; Meyer, Karl

doi:10.1001/archsurg.1959.04320090162026

Cited by 54 publications

(9 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Kozoll evaluated the slides of autopsy studies of liver in patients with cholelithiasis under the various criteria of chronic passive congestion, parenchymatous degeneration, fatty liver, portal cirrhosis, acute hepatitis, toxic hepatitis, biliary cirrhosis, cholangitis. 18 Raven RW in his 77 patients of cholecystitis and cholelithiasis found changes in 47.4%, biliary cirrhosis in 5 patients, cholangiohepatitis in 3 patients, fatty changes in 13 patients and most common inflammatory cell infiltration of periportal tracts in 23 patients and like the present study he also found chiefly lymphocytes. 12 He found periportal fibrosis in 10 patients which is quite high if we compare that with present study.…”

Section: Liver Histopathologysupporting

confidence: 77%

Liver biopsy in gall stone disease: a prospective study in patients undergoing cholecystectomy

et al. 2017

View full text Add to dashboard Cite

Background: Cholelithiasis has affected mankind since many centuries. It not only affects the biliary tree but also has adverse effects on the hepatic parenchyma, which can get further complicated due to infected bile. Early intervention in these cases not only retards the unwanted effects but also prevents irreversible damage to liver. Aim of study was to see the effect of gallstone disease on liver in patients of GSD (Cholelithiasis, Chronic cholecystitis, CBD Stones).Methods: All patients being subjected for planned cholecystectomy were taken as subjects irrespective of age, sex and co-morbid conditions.Results: 90 patients were included in study and they were evaluated for secondary histopathological changes in liver. Abnormal liver histology was seen in 40% of the cases, with portal tract inflammation being the commonest abnormality seen in 24.4% of patients followed by fatty change (17.8%), cholestasis (10%), lobular parenchymal infiltration (8.9%) and one (1.1%) patient had fibrosis. Choledocholithiasis was associated with a greater incidence of positive bile culture (60%) and greater incidence of abnormal liver histology (80%).Conclusions: Gall stone disease cause significant changes in liver histology and these changes are more common in those patients having long duration of symptoms. In patients of choledocholithiasis incidence of infected bile and liver histology changes are more as compared to cholelithiasis with chronic cholecystitis.

show abstract

Section: Liver Histopathologysupporting

confidence: 77%

Liver biopsy in gall stone disease: a prospective study in patients undergoing cholecystectomy

et al. 2017

View full text Add to dashboard Cite

show abstract

“…This confirms reports of Kozoll et al (1959) and Newman and Northup (1959) who found a higher incidence of hepatic disease in patients with gallstones.…”

Section: Commentsupporting

confidence: 92%

“…In 146 cases of choledocholithiasis pancreatic involvement was found in 21.8%. In cholecystitis without stones seven out of 55 patients had pancreatic pathology (Kozoll et al, 1959). Our survey reveals pancreatic pathology in 49 out of 103 patients with cholelithiasis, including five out of nine patients with choledocholithiasis.…”

Section: Commentmentioning

confidence: 70%

See 1 more Smart Citation

Validity of the correlation of gallstones and pancreatic pathology

Erber¹,

Lubowski²,

Levij³

et al. 1972

Gut

View full text Add to dashboard Cite

SUMMARY In a necropsy survey of 724 patients from the Hebrew University Hospital 107 patients were found with gallstones. Ninety-five patients matched according to age and sex served as controls.No difference was found between control and gallstone patients with regard to the incidence and type of pancreatic pathology, except forintestinal metaplasia which was more frequent in the controls.Significantly more pancreatic pathology was found in Ashkenazi-born patients without gallstones than in the respective non-Ashkenazi group. In patients with gallstones no difference in pancreatic pathology was found between the two ethnic groups.Females with gallstones had significantly more hepatic disease than females without gallstones. This difference was not found in males.Hepatic disease alone was associated with a higher incidence of pancreatic pathology.

show abstract

“…46,48 The prevalence rate of cholecystolithiasis in Hispanics (range, 19-40.2%) was higher than the prevalence rates reported for European populations [14][15][16][27][28][29][30][31][32] and higher than those determined from autopsy studies on nonHispanic whites in the United States. 1,65 The risk factors were essentially the same, as in European populations, except for the addition of diabetes mellitus in some studies. With the exception of studies focused on the Hispanic population, no large diagnostic sonography study regarding the prevalence of gallstones has been done in the United States.…”

Section: North and South Americamentioning

confidence: 99%