Pathologic Findings in Lung Volume Reduction Surgery

Evidence of mycobacterial disease in COPD patients with lung volume reduction surgery; the importance of histological assessment of specimens: a cohort study

“…This has been seen in other similar studies [8,12] and is an indication of the pathology that co-exists with severe emphysema.…”

Physiologic Evaluation of the Patient With Lung Cancer Being Considered for Resectional Surgery

“…This discrepant observation from their patients undergoing lobectomy may have been secondary to a relatively small percent age of patients undergoing pneumonectomy being included in their In terms of mid-term and long-term survival, encouraging results have been observed among patients undergoing LVRS and lung cancer resections. 215,218,224 One prospective case-control study found that patients with heterogeneous upper-lobe emphysema who underwent upper lobectomy for known stage I and II lung cancer had a respectable, but lower overall, survival compared with those patients undergoing conventional LVRS resections (57 months vs 88 months, P 5 .06). 218 In contrast, Nakajima et al 226 reported that patients with severe COPD undergoing curative-intent resections for their lung cancers had a worse 5-year survival (24% vs 59%, P , .0001) relative to their patients undergoing more straightforward LVRS.…”

“…214 Anecdotal experience has shown that lung resected during LVRS has occasionally contained unsuspected lung cancers. 215,216 Patients eligible for LVRS who also have lung cancer represent a unique subset of individuals. If traditional criteria are used to determine suitability for resection, most LVRS candidates with lung cancer would not be considered acceptable to proceed with resection.…”

Physiologic Evaluation of the Patient With Lung Cancer Being Considered for Resectional Surgery

“…126 Anecdotal experience has shown that the lung resected during LVRS occasionally contained unsus-pected lung cancers. 127,128 Multiple case series 129 -139 have suggested that patients with extremely poor lung function can tolerate combined LVRS and resection of the lung cancer with an acceptable mortality rate and surprisingly good postoperative outcomes.…”