2013
DOI: 10.14405/kjvr.2013.53.1.001
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Pathological description and immunohistochemical demonstration of ovine abortion associated with Toxoplasma gondii in Iran

Abstract: :The obligatory intracellular protozoan parasite Toxoplasma gondii is a major world wide cause of infectious ovine abortion. In some different diagnostic techniques that are being used to detect this pathogen in ovine fetuses, immunohistochemistry (IHC) is a very sensitive and expensive one. Histopathology is not truly a specific and sensitive test for Toxoplasma infection but it can be helpful to choose some suspected tissues for IHC. In this study 9.5% of 200 samples (aborted ovine fetuses internal organs su… Show more

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Cited by 4 publications
(2 citation statements)
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“…In this study, we successfully developed an IHC technique for Brucella and Chlamydia to identify the presence of the agents in formalin-fixed paraffin-embedded sections of placenta taken from small ruminants experiencing abortion. The immuno-histochemical signal visualized was distinct and consistent with what others have reported for appearance and extent of staining (Ahmed et al, 2012;Rassouli et al, 2013). In all immunohistochemistry positive cases, there was evidence of damage and inflammation in the placenta, consistent with what the agent might cause.…”
Section: Discussionsupporting
confidence: 88%
“…In this study, we successfully developed an IHC technique for Brucella and Chlamydia to identify the presence of the agents in formalin-fixed paraffin-embedded sections of placenta taken from small ruminants experiencing abortion. The immuno-histochemical signal visualized was distinct and consistent with what others have reported for appearance and extent of staining (Ahmed et al, 2012;Rassouli et al, 2013). In all immunohistochemistry positive cases, there was evidence of damage and inflammation in the placenta, consistent with what the agent might cause.…”
Section: Discussionsupporting
confidence: 88%
“…Heart normal. In kidney congestion and degenerative changes (1 sample), hemorrhage (1 sample), PM (2 samples), In the brain most of the findings were similar to what had been recorded in Rassouli et al (2013) such as; severe hyperemia, hemorrhage, edema (2 samples, Figs. 1, 2), different ischemic cell change, myelin degeneration (1 sample) but T. gondii tissue cysts were observed in 2 brain samples for the first time in this outbreak case (Figs.…”
Section: Histopathologysupporting
confidence: 79%