Pathologie, Pathogenese und Therapie des Lungenemphysems

Staehelin, R.

doi:10.1007/978-3-642-90625-1_10

Cited by 5 publications

(1 citation statement)

References 28 publications

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“…The factors which may influence the circulation in emphysema may be classified into four groups according to Fraenkel (2) and Stahelin (3): (1) increased inspiratory position of the lungs; (2) increased intra-alveolar pressure; (3) obliteration of the pulmonary capillaries; (4) alterations in rate and depth of respiration. Since the first and fourth points are closely related, they wil be discussed together.…”

Section: Rpsuma Of Literature On the Inluence Of Mechanical Factors Imentioning

confidence: 99%

Studies on the Velocity of Blood Flow

Weiss¹,

Blumgart²

1927

J. Clin. Invest.

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Pulmonary emphysema frequently presents one of the most perplexing problems of differential diagnosis in clinical medicine because the cardinal symptoms, dyspnea, cough, and cyanosis are characteristic also of circulatory insufficiency. In many patients, the history and signs of cardiac pathology enable one to make a diagnosis of cardiovascular disease with confidence; but in others, with little or no evidence of heart disease and with no signs of peripheral congestion, the problem arises as to whether the dyspnea of the patient is due to early myocardial failure or to the disordered gaseous exchange of pulmonary emphysema. Frequently, the problem is still further complicated by the simultaneous presence of both conditions. It then becomes a matter of considerable clinical importance to estimate the relative significance of these two conditions in producing the cough, dyspnea, and lowered vital capacity, because proper treatment and accurate prognosis require such differentiation (1).Unfortunately, our knowledge of the underlying pathological physiology of pulmonary emphysema, upon which rational diagnosis and therapeutics must be based, is incomplete. Studies on the circulation in patients suffering from pulmonary emphysema are especially lacking since direct measurement of the blood flow through the lungs has hitherto been impossible, and because other data on

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Section: Rpsuma Of Literature On the Inluence Of Mechanical Factors Imentioning

confidence: 99%