Pathomorphology and pathogenic role of myocardial bridges in sudden cardiac death

Descrição morfológica e implicações clínicas de pontes miocárdicas: um estudo anatômico em colombianos

“…Mean MB thickness in our study was 1.54 mm. This represents a mid-point amongst the results reported by other authors (3, 2.5, 1.8, 1.2, and 0.9 mm) 24,28,29,38,39 . MB length, thickness and number are variables that must be considered in the cardiac pathophysiology of different diseases; however, it is equally likely that MB does not produce any effects.…”

“…These PBB actually could be generated currently by a MB. Rosenberg and Nepomnyashchikh 39 have stated that the hemodynamics of coronary arteries with MB change due to obstructed flow and turbulence, producing collateral arterial compensation, which (according to the authors), prevent MB atheroma production40,41. It will be interesting to observe the presence of PBB and their biometrics in angiographic studies in the pediatric population.…”

Characterisation of myocardial bridges in pigs: a comparative anatomical analysis with the human heart

“…Reports on the thickness of MB in pigs have not included means, but ranges (0.8-4.7 mm) [1,22], thus making difficult to qualify our finding (1.13 mm) as similar or dissimilar to the findings of the studies described. Upon comparison of the thickness of the MB in humans, the majority of the studies reveal mean thicknesses in the range of 1.2-2.5 mm [16,20,24,28,30]. Several reports confirm the influence of MB in the aetiology and pathogeny of ischaemic episodes of the heart [4,19,22].…”

“…Concerning the site of occurrence, in pigs MB have been described especially in the middle third of the SIA [21], whereas in humans they are described more often at the level of the medium and upper thirds of the anterior interventricular artery (AIA) [3,24,27,30,31].…”

“…A high percentage of MB are asymptomatic, but their morphologic features such as length, depth, and location on one or several arterial branches, in addition to some other variables, may result in the occurrence of diverse ischaemic or arrhythmic conditions of the heart that could become the cause of sudden deaths observed among pigs [11,14,30].…”