“…Although SANS serves as one of the largest potential physiologic and pathologic barriers to future crewed interplanetary LDSF by the National Aeronautics and Space Administration (NASA), the underlying mechanism of SANS remains ill defined. 4 However, oxidative stress has been proposed as one of the contributory mechanisms underlying SANS 5 . In this article, we will focus on the ocular oxidative biomarker changes during spaceflight and its implications for ocular health.…”