Patient Adaptive Neurofeedback for ADHD Therapy

Schmidt, Thorsten; Henrich, D.

doi:10.1515/bmt-2012-4444

Cited by 1 publication

(1 citation statement)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Up to now, predominantly electroencephalography was used for neurofeedback, e.g. in patients with attention deficit/hyperactivity disorder [ 13 , 14 , 15 , 16 , 17 ], for the communication with severely paralysed patients [ 18 , 19 , 20 , 21 ], or to suppress epileptic activity [ 22 ]. However, with EEG-neurofeedback it is difficult to modulate the activity in small brain areas because of the low spatial resolution.…”

Section: Literaturementioning

confidence: 99%

Modulation of Craving Related Brain Responses Using Real-Time fMRI in Patients with Alcohol Use Disorder

et al. 2015

View full text Add to dashboard Cite

LiteratureOne prominent symptom in addiction disorders is the strong desire to consume a particular substance or to display a certain behaviour (craving). Especially the strong association between craving and the probability of relapse emphasises the importance of craving in the therapeutic process. Neuroimaging studies have shown that craving is associated with increased responses, predominantly in fronto-striatal areas.Aim and MethodsThe aim of the present study is the modification of craving-related neuronal responses in patients with alcohol addiction using fMRI real-time neurofeedback. For that purpose, patients with alcohol use disorder and healthy controls participated once in neurofeedback training; during the sessions neuronal activity within an individualized cortical region of interest (ROI) (anterior cingulate cortex, insula, dorsolateral prefrontal cortex) was evaluated. In addition, variations regarding the connectivity between brain regions were assessed in the resting state.Results and DiscussionThe results showed a significant reduction of neuronal activity in patients at the end of the training compared to the beginning, especially in the anterior cingulate cortex, the insula, the inferior temporal gyrus and the medial frontal gyrus. Furthermore, the results show that patients were able to regulate their neuronal activities in the ROI, whereas healthy subjects achieved no significant reduction. However, there was a wide variability regarding the effects of the training within the group of patients. After the neurofeedback-sessions, individual craving was slightly reduced compared to baseline. The results demonstrate that it seems feasible for patients with alcohol dependency to reduce their neuronal activity using rtfMRI neurofeedback. In addition, there is some evidence that craving can be influenced with the help of this technique.Future ProspectsIn future, real-time fMRI might be a complementary neurophysiological-based strategy for the psychotherapy of patients with psychiatric or psychosomatic diseases. For that purpose, the stability of this effect and the generalizability needs to be assessed.

show abstract