Patients with burning mouth sensations. A clinical investigation of causative factors in a group of “compete denture wearers” Jordanian population

Mukatash-Nimri, Gadeer Elea; Alnimri, M; Al-Jadeed, Omar G.; Al-Zobe, Zaid R.; Abu-Rumman, Khuzama K.; Masarwa, Nader

doi:10.1016/j.sdentj.2016.10.002

Cited by 3 publications

(1 citation statement)

References 20 publications

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“…This syndrome is frequently accompanied by xerostomia and dysgeusia 1 . The burning sensation often occurs in various sites such as tongue, palate, throat and prosthesis support areas 2 …”

Section: Introductionmentioning

confidence: 99%

Evaluation of IL‐6 levels and +3954 polymorphism of IL‐1β in burning mouth syndrome: A systematic review and meta‐analysis

Campello

Pellizzer

Vasconcelos

et al. 2020

J Oral Pathology Medicine

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This study evaluated IL‐6 salivary levels as well as the +3954 polymorphism of IL‐1β in patients with burning mouth syndrome and healthy individuals, through case‐control studies. This systematic review and meta‐analysis followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines. We conducted this research in PubMed/MEDLINE, Cochrane Library and Web of Science databases. The risk of bias was measured based in the Newcastle‐Ottawa Scale. Researches with a group of patients with burning mouth syndrome and a control group in which the presence of the +3954 polymorphism of IL‐1β and/ or IL‐6 salivary levels through non‐stimulated saliva were evaluated to detect if this interleukin concentrations are increased in patients and if the polymorphism is a risk factor for this syndrome. We identified seven studies with total of 440 participants, 229 patients with burning mouth syndrome and 211 healthy controls, ages 24‐84 years old. The female gender was predominant. Patients in the majority of studies did not present increased levels of IL‐6 and the +3954 polymorphism of IL‐1β is not a risk factor for this syndrome. A few studies researched biomarkers in this pathology and more investigations are required not only to identify salivary levels and the polymorphism evaluated, but also other interleukins and polymorphisms in order to clarify the etiopathogenesis of this syndrome as well as for propose new diagnostic methods and treatments.

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“…This syndrome is frequently accompanied by xerostomia and dysgeusia 1 . The burning sensation often occurs in various sites such as tongue, palate, throat and prosthesis support areas 2 …”

Section: Introductionmentioning

confidence: 99%

Evaluation of IL‐6 levels and +3954 polymorphism of IL‐1β in burning mouth syndrome: A systematic review and meta‐analysis

Campello

Pellizzer

Vasconcelos

et al. 2020

J Oral Pathology Medicine

View full text Add to dashboard Cite

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Challenge in the diagnosis, evaluation, and management of burning mouth sensation

Wu¹,

Zhang²,

Wang³

et al. 2023

The Journal of the American Dental Association

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The Association of Elevated Serum IgE and Xerostomia with Recurrent Aphthous Stomatitis

Shamahy¹

2019

OJDOH

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Background and objectives: Recurrent Aphthous Stomatitis (RAS) is one of the most common oral mucosal diseases. This study aimed to determine the prevalence of RAS, the association of Immunoglobulin E with RAS and potential risk factors of RAS in patients at dental clinics of Sana'a universities in Sana'a city, Yemen. Subjects and methods:A cross-sectional study was conducted from January to December 2017 and includes 2164 patients. The patients interviewed and examined by dentists and 72 were clinically diagnosed to have RAS. The patients with RAS responded to a questionnaire that included demographic background, Qat chewing habits, smoking habits, history and course of RAS episodes. They were also subjected to laboratory tests, including determination of serum IgE levels and xerostomia. Results:The crude prevalence of RAS was 3.3%; female prevalence was 3.8% slightly higher than 2.4% of the male. There was a higher rate of RAS in age group 16-25 years (12.3%) and age group 26-35 years (9.3%) with OR=7 times and 4.1 times respectively (p<0.001). While lower rates of RAS were occurred in children under 15 years (0.41%) and older age (0.4%), (<0.001). The Mean±SD of IgE level for major RAS patients was 233±15.3IU/ml; while for minor was 127±17.3IU/ml. There was association between elevated IgE, Xerostomia, smoking habit, and chewing Qat and occurrence of major RAS (OR=6.4, 3.3, 26.8,and 7.1 respectively). Conclusion:Elevated IgE levels and xerostomia may be considered as part of the RAS patient's work-up. Further research is needed to identify biological mechanisms that account for the observed associations.

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Patients with burning mouth sensations. A clinical investigation of causative factors in a group of “compete denture wearers” Jordanian population

Abstract: Spontaneous symptoms of burning mouth without mucosal signs should be considered as a manifestation of undermind pathology and/or distress, and the multi-factorial causes of burning mouth syndrome and sensation need to be referred to the suitable specialist for better treatment results.

Cited by 3 publications

References 20 publications

Evaluation of IL‐6 levels and +3954 polymorphism of IL‐1β in burning mouth syndrome: A systematic review and meta‐analysis

Evaluation of IL‐6 levels and +3954 polymorphism of IL‐1β in burning mouth syndrome: A systematic review and meta‐analysis

Challenge in the diagnosis, evaluation, and management of burning mouth sensation

The Association of Elevated Serum IgE and Xerostomia with Recurrent Aphthous Stomatitis

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